Lysosome is the central organelle for intracellular degradation of biological macromolecules
and organelles. The material destined for degradation enters the lysosomes primarily via …

Lysosomes serve as the cellular recycling centre and are filled with numerous hydrolases
that can degrade most cellular macromolecules. Lysosomal membrane permeabilization …

For many years apoptosis research has focused on caspases and their putative role as sole
executioners of programmed cell death. Accumulating information now suggests that …

Lysosomal membrane permeabilization (LMP) occurs in response to a large variety of cell
death stimuli causing release of cathepsins from the lysosomal lumen into the cytosol where …

The endocytic pathway is a system specialized for the uptake of compounds from the cell
microenvironment for their degradation. It contains an arsenal of hydrolases, including …

Lysosome is a highly membrane-bound organelle which possesses a sequence of
biological functions including protein degradation, cell signal transduction, plasma …

From the‡ Department of Biochemistry and Molecular and Structural Biology, Jozef Stefan
Institute and the § Faculty of Chemistry and Chemical Technology, University of Ljubljana, SI …

Lysosomes are specialized organelles for protein recycling and as such are involved in the
terminal steps of autophagy. However, it has become evident that lysosomes also play an …

Lysosomes are the key degradative compartments of the cell. Lysosomal cathepsins, which
are enclosed in the lysosomes, help to maintain the homeostasis of the cell's metabolism by …

Lysosomes are acidic organelles that are involved in cellular digestion by endocytosis,
phagocytosis, and autophagy. They contain more than 50 hydrolases that are capable of …