Current and emerging therapies for corneal neovascularization

D Roshandel, M Eslani, A Baradaran-Rafii… - The ocular …, 2018 - Elsevier
The cornea is unique because of its complete avascularity. Corneal neovascularization
(CNV) can result from a variety of etiologies including contact lens wear; corneal infections; …

[HTML][HTML] Corneal neovascularization and biological therapy

OB Voiculescu, LM Voinea… - Journal of medicine and …, 2015 - ncbi.nlm.nih.gov
Corneal avascularity is necessary for the preservation of optimal vision. The cornea
maintains a dynamic balance between pro-and antiangiogenic factors that allows it to …

Treatments for corneal neovascularization: a review

D Gupta, C Illingworth - Cornea, 2011 - journals.lww.com
Corneal neovascularization (CNV) may be a physiological response to various stimuli, but a
chronic and persistent upregulation of neoangiogenesis can result in pathological CNV …

Corneal neovascularization and the utility of topical VEGF inhibition: ranibizumab (Lucentis) vs bevacizumab (Avastin)

W Stevenson, SF Cheng, MH Dastjerdi, G Ferrari… - The ocular …, 2012 - Elsevier
Corneal avascularity is necessary for the preservation of optimal vision. The cornea
maintains a dynamic balance between pro-and antiangiogenic factors that allows it to …

Corneal neovascularization: molecular events and therapeutic options

Y Shakiba, K Mansouri, D Arshadi… - Recent patents on …, 2009 - ingentaconnect.com
Corneal neovascularization (NV) is a significant complication of numerous infectious and
non-infectious ocular surface disorders. Presence of newly formed blood vessels in the …

[HTML][HTML] Up-to-date molecular medicine strategies for management of ocular surface neovascularization

Y Yang, J Zhong, D Cui, LD Jensen - Advanced Drug Delivery Reviews, 2023 - Elsevier
Ocular surface neovascularization and its resulting pathological changes significantly alter
corneal refraction and obstruct light path to the retina, and hence is a major cause of vision …

Horizons in therapy for corneal angiogenesis

S Maddula, DK Davis, S Maddula, MK Burrow… - Ophthalmology, 2011 - Elsevier
Corneal neovascularization can lead to a devastating disease process that involves the
breakdown of the limbal barrier and the formation of blood vessels in the cornea, leading to …

Corneal neovascularization: an anti-VEGF therapy review

JH Chang, NK Garg, E Lunde, KY Han, S Jain… - Survey of …, 2012 - Elsevier
Corneal neovascularization is a serious condition that can lead to a profound decline in
vision. The abnormal vessels block light, cause corneal scarring, compromise visual acuity …

Therapeutic approaches for corneal neovascularization

S Feizi, AA Azari, S Safapour - Eye and Vision, 2017 - Springer
Angiogenesis refers to new blood vessels that originate from pre-existing vascular
structures. Corneal neovascularization which can lead to compromised visual acuity occurs …

Corneal neovascularization

MP Nicholas, N Mysore - Experimental eye research, 2021 - Elsevier
The optical clarity of the cornea is essential for maintaining good visual acuity. Corneal
neovascularization, which is a major cause of vision loss worldwide, leads to corneal …