Mechanisms and regulation of endothelial VEGF receptor signalling

M Simons, E Gordon, L Claesson-Welsh - Nature reviews Molecular …, 2016 - nature.com
Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) are uniquely
required to balance the formation of new blood vessels with the maintenance and …

VEGF signaling inside vascular endothelial cells and beyond

A Eichmann, M Simons - Current opinion in cell biology, 2012 - Elsevier
Vascular endothelial growth factor-A (VEGF-A) has long been recognized as the key
regulator of vascular development and function in health and disease. VEGF is a secreted …

VEGF receptor signalling? In control of vascular function

AK Olsson, A Dimberg, J Kreuger… - … reviews Molecular cell …, 2006 - nature.com
Vascular endothelial growth-factor receptors (VEGFRs) regulate the cardiovascular system.
VEGFR1 is required for the recruitment of haematopoietic precursors and migration of …

Signal transduction by vascular endothelial growth factor receptors

S Koch, S Tugues, X Li, L Gualandi… - Biochemical …, 2011 - portlandpress.com
VEGFs (vascular endothelial growth factors) control vascular development during
embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There …

Signal transduction by vascular endothelial growth factor receptors

S Koch, L Claesson-Welsh - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Vascular endothelial growth factors (VEGFs) are master regulators of vascular development
and of blood and lymphatic vessel function during health and disease in the adult. It is …

Vascular endothelial growth factor signaling in development and disease

S Karaman, VM Leppänen, K Alitalo - Development, 2018 - journals.biologists.com
Vascular endothelial growth factors (VEGFs) are best known for their involvement in
orchestrating the development and maintenance of the blood and lymphatic vascular …

An inside view: VEGF receptor trafficking and signaling

M Simons - Physiology, 2012 - journals.physiology.org
Vascular endothelial growth factors (VEGF) and their receptors play a central role in the
development of cardiovascular system and in vasculature-related processes in the adult …

[HTML][HTML] VEGFR-1 and VEGFR-2: two non-identical twins with a unique physiognomy

N Rahimi - Frontiers in bioscience: a journal and virtual library, 2006 - ncbi.nlm.nih.gov
Angiogenesis involves endothelial cell differentiation, proliferation, migration and cord
formation, which lead to tubulogenesis to form vessels. One group of growth factor receptors …

VEGF-A/VEGFR2 signaling network in endothelial cells relevant to angiogenesis

CS Abhinand, R Raju, SJ Soumya, PS Arya… - Journal of cell …, 2016 - Springer
Vascular endothelial growth factor-A (VEGF-A) is essential for endothelial cell functions
associated with angiogenesis. Signal transduction networks initiated by VEGFA/VEGFR2 …

Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family

I Zachary, G Gliki - Cardiovascular research, 2001 - academic.oup.com
The central role of vascular endothelial growth factor (VEGF) in angiogenesis in health and
disease makes it attractive both as a therapeutic target for anti-angiogenic drugs and as a …