Objective To determine genome-wide DNA methylation profiles of knee cartilage from
patients with Kashin-Beck disease (KBD) and osteoarthritis (OA). Method Knee cartilage …

Abstract Background Kashin-Beck disease (KBD) is an endemic osteochondropathy of
unknown etiology. Osteoarthritis (OA) is a form of degenerative joint disease sharing similar …

Objective Epigenetic modifications of DNA are regarded as a crucial factor for understanding
the molecular basis of complex phenotypes. This study aims to uncover insight into the …

Kashin–Beck disease (KBD) is a degenerative osteoarticular disorder, and displays the
significant differences with osteoarthritis (OA) regarding the etiology and molecular changes …

To understand how differentially methylated genes (DMGs) might affect the pathogenesis of
Kashin-Beck disease (KBD). Genome-wide methylation profiling of whole blood from 12 …

Kashin-Beck disease (KBD) is an endemic chronic osteochondropathy. The etiology of KBD
remains unknown. In this study, we conducted an integrative analysis of genome-wide DNA …

Objective To perform a genome‐wide DNA methylation study to identify differential DNA
methylation patterns in subchondral bone underlying eroded and intact cartilage from …

Objective To perform a genome‐wide DNA methylation study to identify DNA methylation
changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially …

Background Evidence suggests that epigenetics plays a role in osteoarthrits (OA). The aim
of the study was to describethe genome wide DNA methylation changes in hip and knee OA …

Background Researches indicate that epigenetics was involved in osteoarthritis (OA). The
purpose of this study was to describe the alterations of DNA methylation in hip and knee OA …