Objective To explore the association between oxidative stress (OS) and Kashin-Beck
disease (KBD). Methods Terms associated with “KBD” and “OS” were searched in the six …

Background and objective Ankylosing spondylitis is a chronic inflammatory disease
characterized by inflammation of the sacroiliac joints and the spine that can lead to …

Objectives To compare the epigenetic landscape of 3D cell models of human primary
articular chondrocytes (hPACs) and human bone-marrow derived mesenchymal stem cells …

Objective To identify methylation quantitative trait loci (mQTL s) correlating with osteoarthritis
(OA) risk alleles and to undertake mechanistic characterization as a means of target gene …

Background: Osteoarthritis (OA) is a kind of chronic osteoarthropathy and degenerative joint
disease. Epigenetic regulation in the gene expression dynamics has become increasingly …

Abstract Purpose Kashin-Beck disease (KBD) is an endemic degenerative osteoarthritis
associated with extracellular matrix degradation. The aim of this investigation was to …

Osteoarthritis (OA) is chronic arthritis characterized by articular cartilage degradation.
However, a comprehensive regulatory network for OA-related microRNAs and DNA …

Osteoarthritis (OA) is a chronic musculoskeletal disease characterised by the destruction of
articular cartilage, synovial inflammation and bone remodelling. Disease aetiology is …

Worldwide, osteoarthritis (OA) affects approxi‑mately 40% of people older than 70 years and
is therefore the most common form of arthritis. OA is a complex degenerative disease of the …

Rheumatoid arthritis (RA) is a chronic, systemic inflammatory disease of unknown origin,
which exhibits a complex heterogeneity in its pathophysiological background, resulting in …