Introduction The biological membranes as natural permeable barriers are required for
survival and function of living cells. However, these natural barriers could be a major …

Cell-penetrating peptides (CPPs) are oligopeptides that can permeate the cell membrane.
The use of a CPP-mediated transport system could be an excellent method for delivering …

Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult
challenge. The cellular membrane is very effective in its role as a selectively permeable …

The selective permeability of the plasma membrane prohibits most exogenous agents from
gaining cellular access. Since many therapeutics and reporter molecules must be …

Cell-penetrating peptides (CPPs) can cross cellular membranes in a non-toxic fashion,
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …

ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …

In today's modern era of medicine, macromolecular compounds such as proteins, peptides
and nucleic acids are dethroning small molecules as leading therapeutics. Given their …

The recent discovery of new potent therapeutic molecules that do not reach the clinic due to
poor delivery and low bioavailability have made of delivery a key stone in therapeutic …

The plasma membrane as a selectively permeable barrier of living cells is essential to cell
survival and function. In many cases, however, the efficient passage of exogenous bioactive …

Abstracts Cell-penetrating peptides (CPPs), also known as protein transduction domains,
are a class of diverse amino acid sequences with the ability to cross cellular membranes …