An attempt will be made to provide a short conceptual review to integrate, from an
evolutionary perspective, how the emergence of gap junctional intercellular communication …

In multicellular organisms, the role of gap junction intercellular communication (GJIC) in the
regulation of cell proliferation, cell differentiation, and apoptosis is becoming increasingly …

The discovery of the gap junction structure, its functions and the family of the “connexin”
genes, has been basically ignored by the major biological disciplines. These connexin …

While many theories have been proposed for the aging process, and many debates on the
matter of aging and the diseases of aging being either the result of the same or independent …

In spite of the early speculation by Loewenstein that one of the critical distinguishing
phenotypes of cancers from normal cells was the dysfunction of gap junctional intercellular …

Stem cells provide an invaluable tool to develop cell replacement therapies for a range of
serious disorders caused by cell damage or degeneration. Much research in the field is …

Gap Junction-Mediated Intercellular Signalling in Health and Disease Chairman: Norton B.
Gilula 1999 The last few years have seen considerable progress in this field, and exciting …

Understanding the process of carcinogenesis will involve both the accumulation of many
scientific facts derived from molecular, biochemical, cellular, physiological, whole animal …

In this review, a stem cell concept, initially defined by the author more than 10 years ago
focusing on neural stem cells, has been systematically refined and updated. Relative to the …

Modern technologies in the biomedical field have opened new avenues to the
understanding of developmental processes. Various stem cell lines established in vitro …