[HTML][HTML] Melanin deposition in two Cryptococcus species depends on cell-wall composition and flexibility

C Chrissian, E Camacho, MS Fu… - Journal of Biological …, 2020 - ASBMB
Cryptococcus neoformans and Cryptococcus gattii are two species complexes in the large
fungal genus Cryptococcus and are responsible for potentially lethal disseminated …

Melanin and virulence in Cryptococcus neoformans

A Casadevall, AL Rosas, JD Nosanchuk - Current opinion in microbiology, 2000 - Elsevier
Melanin synthesis has been associated with virulence for the human pathogenic fungus
Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize …

Budding of melanized Cryptococcus neoformans in the presence or absence of l-dopa

JD Nosanchuk, A Casadevall - Microbiology, 2003 - microbiologyresearch.org
Cryptococcus neoformans is a pathogenic fungus that produces melanin when incubated in
the presence of certain phenolic substrates such as l-3, 4-dihydroxyphenylalanine (l-dopa) …

[HTML][HTML] The structural unit of melanin in the cell wall of the fungal pathogen Cryptococcus neoformans

E Camacho, R Vij, C Chrissian… - Journal of Biological …, 2019 - ASBMB
Melanins are synthesized macromolecules that are found in all biological kingdoms. These
pigments have a myriad of roles that range from microbial virulence to key components of …

Cryptococcus neoformans melanin and virulence: mechanism of action

Y Wang, P Aisen, A Casadevall - Infection and immunity, 1995 - Am Soc Microbiol
Black melanin-like pigments are produced by several neurotropic fungi, including
Cryptococcus neoformans. Pigment production is associated with virulence. In media …

[HTML][HTML] Solid-state NMR spectroscopy identifies three classes of lipids in Cryptococcus neoformans melanized cell walls and whole fungal cells

C Chrissian, E Camacho, JE Kelly, H Wang… - Journal of Biological …, 2020 - ASBMB
A primary virulence-associated trait of the opportunistic fungal pathogen Cryptococcus
neoformans is the production of melanin pigments that are deposited into the cell wall and …

[HTML][HTML] Role of Cln1 during melanization of Cryptococcus neoformans

R García-Rodas, N Trevijano-Contador… - Frontiers in …, 2015 - frontiersin.org
Cryptococcus neoformans is an opportunistic fungal pathogen that has several well-
described virulence determinants. A polysaccharide capsule and the ability to produce …

Melanization of Cryptococcus neoformans in murine infection

JD Nosanchuk, P Valadon, M Feldmesser… - … and cellular biology, 1999 - Am Soc Microbiol
Cryptococcus neoformans is a fungus that is pathogenic in humans and that can produce
melanin in vitro. Melanization is associated with virulence, but there is no evidence that …

Melanization in Cryptococcus neoformans requires complex regulation

RJB Cordero, E Camacho, A Casadevall - MBio, 2020 - Am Soc Microbiol
The fungal human pathogen Cryptococcus neoformans undergoes melanization in
response to nutrient starvation and exposure to exogenous melanin precursors …

Cell-wall dyes interfere with Cryptococcus neoformans melanin deposition

R Perez-Dulzaides, E Camacho… - …, 2018 - microbiologyresearch.org
Melanization is an intrinsic characteristic of many fungal species, but details of this process
are poorly understood because melanins are notoriously difficult pigments to study. While …