Wnt–β-catenin signalling in liver development, health and disease

MJ Perugorria, P Olaizola, I Labiano… - Nature reviews …, 2019 - nature.com
The canonical Wnt–β-catenin pathway is a complex, evolutionarily conserved signalling
mechanism that regulates fundamental physiological and pathological processes. Wnt–β …

[HTML][HTML] WNT/β-catenin signaling in the development of liver cancers

S He, S Tang - Biomedicine & Pharmacotherapy, 2020 - Elsevier
The WNT/β-catenin signaling pathway is a highly conserved and tightly controlled molecular
mechanism that regulates embryonic development, cellular proliferation and differentiation …

The Wnt/β-catenin signaling pathway in liver biology and disease

J Behari - Expert review of gastroenterology & hepatology, 2010 - Taylor & Francis
The Wnt signaling pathway is an evolutionarily conserved, highly complex signaling
pathway that is critical for development, differentiation and cellular homeostasis. The protein …

Wnt/β-catenin signaling in hepatic organogenesis

K Nejak-Bowen, SPS Monga - Organogenesis, 2008 - Taylor & Francis
Wnt/β-catenin signaling has come to the forefront of liver biology in recent years. This
pathway regulates key pathophysiological events inherent to the liver including …

Wnt signaling in liver cancer

Y Takigawa, A Brown - Current drug targets, 2008 - ingentaconnect.com
Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide. As in many
other types of cancer, aberrant activation of the canonical Wnt/β-catenin signaling pathway …

Wnt/β-catenin signaling in liver development, homeostasis, and pathobiology

JO Russell, SP Monga - Annual Review of Pathology …, 2018 - annualreviews.org
The liver is an organ that performs a multitude of functions, and its health is pertinent and
indispensable to survival. Thus, the cellular and molecular machinery driving hepatic …

Role of Wnt/β-catenin signaling in liver metabolism and cancer

SPS Monga - The international journal of biochemistry & cell biology, 2011 - Elsevier
Wnt/β-catenin signaling is known for its role in embryogenesis as well as carcinogenesis. In
the liver, it plays many critical roles during hepatic development and regeneration, and its …

[PDF][PDF] WNT/β‐catenin signaling in liver health and disease

MD Thompson, SPS Monga - Hepatology, 2007 - Wiley Online Library
Wnt/β‐catenin signaling is emerging as a forerunner for its critical roles in many facets of
human biology. Its roles in embryogenesis, organogenesis, and maintaining tissue and …

Wnt/β-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology

C Cavard, S Colnot, V Audard, S Benhamouche… - 2008 - Future Medicine
The Wnt/β-catenin pathway is a key developmental pathway for which alterations have been
described in various human cancers. The aberrant activation of this pathway is a major …

Wnt/β-catenin signaling in liver cancers

W Wang, R Smits, H Hao, C He - Cancers, 2019 - mdpi.com
Liver cancer is among the leading global healthcare issues associated with high morbidity
and mortality. Liver cancer consists of hepatocellular carcinoma (HCC), cholangiocarcinoma …