Secretory vesicle exocytosis is a fundamental biological event and the process by which
hormones (like insulin) are released into the blood. Considerable progress has been made …

Exocytosis, the merger of the vesicle membrane with the plasma membrane, is thought to
mediate the release of hormones and neurotransmitters from secretory vesicles. The work of …

The focus of this special issue (SI)» Membrane Merger in Conventional and Unconventional
Vesicle Secretion «is regulated exocytosis, a universally conserved mechanism, consisting …

Regulated exocytosis, which involves fusion of secretory vesicles with the plasma
membrane, is an important mode of communication between cells. In this process, signalling …

Type 2 diabetes is caused by defects in both insulin sensitivity and insulin secretion.
Glucose triggers insulin secretion by causing exocytosis of insulin granules from pancreatic …

Cholesterol is essential for exocytosis in secretory cells, but the exact molecular mechanism
by which it facilitates exocytosis is largely unknown. Distinguishing contributions from the …

The regulated secretory pathway in neuroendocrine cells ends with the release of hormones
and neurotransmitters following a rise in cytosolic calcium. This process known as regulated …

infrastructurel techniques have shown that an early event in the exocytotic fusion of a
secretory vesicle is the formation of a narrow, water-filled pore spanning both the vesicle …

In the past, vesicle content release was thought to occur immediately and completely after
triggering of exocytosis. However, vesicles may merge with the plasma membrane to form …

Exocytosis is a multistage process involving a merger between the vesicle and the plasma
membranes, leading to the formation of a fusion pore, a channel, through which secretions …