Efficacy and safety of biologics and small molecules for psoriasis in pediatric and geriatric populations. Part I: focus on pediatric patients

M Megna, E Camela, T Battista, L Genco… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Psoriasis management is challenging, especially in pediatric age for different
factors. The introduction of biologic drugs and oral small molecules (OSM) revolutionized the …

Efficacy and safety of biologics and small molecules for psoriasis in pediatric and geriatric populations. Part II: focus on elderly patients

M Megna, E Camela, T Battista, L Genco… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The management of moderate-to-severe forms of psoriasis is becoming a
frequent concern in geriatric age due to the higher risk to develop treatment adverse events …

Management of pediatric plaque psoriasis using biologics

P Lansang, JN Bergman, L Fiorillo, M Joseph… - Journal of the American …, 2020 - Elsevier
Background Psoriasis is a chronic inflammatory disease with clinical manifestations of the
skin that affect adults and children. In adults, biologics have revolutionized the treatment of …

Biological treatments for pediatric psoriasis: state of the art and future perspectives

F Diotallevi, O Simonetti, G Rizzetto, E Molinelli… - International Journal of …, 2022 - mdpi.com
Psoriasis is a chronic systemic inflammatory disease that primarily affects the skin and is
associated with multiple comorbidities with a considerable reduction in quality of life of …

Biologic treatment algorithms for moderate-to-severe psoriasis with comorbid conditions and special populations: a review

A Thatiparthi, A Martin, J Liu, A Egeberg… - American Journal of …, 2021 - Springer
The emergence of data from clinical trials of biologics, the approval of new biologics, and
our improved understanding of psoriasis pathogenesis have increased the therapeutic …

Systemic treatment of pediatric psoriasis: a review

M Napolitano, M Megna, A Balato, F Ayala… - Dermatology and …, 2016 - Springer
Psoriasis is a chronic, immune-mediated, inflammatory skin disease, affecting 1–3% of the
white population. Although the existence of two psoriasis incidence peaks has been …

Pediatric psoriasis: From new insights into pathogenesis to updates on treatment

HO Kim, SY Kang, JC Kim, CW Park, BY Chung - Biomedicines, 2021 - mdpi.com
Psoriasis is a chronic inflammatory systemic disease primarily affecting the skin, but which
often involves considerable comorbidities as well. One-third of psoriasis cases start during …

Psoriasis in children

R Pinson, B Sotoodian, L Fiorillo - Psoriasis: Targets and Therapy, 2016 - Taylor & Francis
The clinical presentation, disease associations, and diverse treatment modalities in
overcoming the challenges of managing pediatric psoriasis have been extensively …

Treating psoriasis in the elderly: biologics and small molecules

M Megna, L Potestio, G Fabbrocini… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Psoriasis prevalence in the elderly is growing. It is estimated that 15% of elderly
psoriasis patients suffer from moderate-to-severe disease, thus requiring systemic …

Treatment of severe psoriasis in children: recommendations of an Italian expert group

AB Fortina, F Bardazzi, S Berti, C Carnevale… - European Journal of …, 2017 - Springer
This article provides comprehensive recommendations for the systemic treatment of severe
pediatric psoriasis based on evidence obtained from a systematic review of the literature …