METHODS: We searched the provincial pathology database with “adenocarcinoma” in the
colorectal specimen pathology reports between March 2018 and December 2020. We cross …

Lynch syndrome, also known as hereditary non-polyposis colorectal cancer (HNPCC), is the
most common form of inherited colorectal cancer (CRC). Affected individuals need to …

To the Editor: We read with great interest the recently published article about the guidelines
on genetic evaluation and management of Lynch syndrome (LS) by the prestigious US multi …

Abstract Background Identification of Lynch syndrome (LS) followed by annual/biannual
surveillance colonoscopy markedly reduces the risk of developing new colorectal cancer …

Background Lynch syndrome is the most common cause of hereditary colorectal cancer
(CRC) and confers increased risk of other cancers. Identification of patients improves …

Background & Aims Screening of persons with newly diagnosed colorectal cancer for Lynch
syndrome can yield substantial benefits at acceptable costs, presuming sufficient uptake of …

Context Lynch syndrome is the most common form of hereditary colorectal cancer (CRC)
and is caused by germline mutations in DNA mismatch repair (MMR) genes. Identification of …

Background: Lynch syndrome (LS) due to an inherited damaging mutation in mismatch
repair (MMR) genes comprises 3% of all incident colorectal cancer (CRC). Molecular testing …

Purpose Lynch syndrome (LS) is a hereditary condition that increases one's risk of
developing colorectal, endometrial, and other extracolonic cancers. MD Anderson Cancer …

Universal tumor screening (UTS) for Lynch syndrome (LS) on colorectal cancer (CRC) can
be performed on biopsies or resection specimens. The advantage of biopsies is the chance …