Degeneration of retinal pigment epithelial (RPE) cells is a clinical hallmark of age-related
macular degeneration (AMD), the leading cause of blindness among aged people in the …

Plant-derived polyphenols are known to possess anti-inflammatory and antioxidant effects.
In recent years, several studies have investigated their potential benefits for treating chronic …

purpose. To determine whether specific dietary and synthetic flavonoids can protect human
retinal pigment epithelial (RPE) cells from oxidative-stress–induced death. methods. The …

Purpose: Oxidative stress has been suggested to be a major risk factor for the pathogenesis
of AMD. Retinal pigment epithelial (RPE) cells are essential for maintaining the homeostasis …

Purpose To investigate the effects of inflammatory factors and oxidative stress on cell
survival of the human retinal pigment epithelial (RPE) cell line, ARPE-19. Methods Confluent …

Purpose Oxidative injury to the retinal pigment epithelium (RPE) has been proposed to play
a contributing role in age-related macular degeneration (AMD). Exposure to solar ultraviolet …

The risk of chronic oxidative stress in the retinal pigment epithelium (RPE) increases with
age due to accumulation of the photoreactive age pigment lipofuscin (LFG). Here, we asked …

Oxidative stress serves a vital function in the pathogenesis of age‑related macular
degeneration (AMD); genipin (GP) possesses antioxidative properties. The present study …

Retinal pigment epithelium (RPE) plays the principal role in age-related macular
degeneration (AMD), a progressive eye disease with no cure and limited therapeutical …

Purpose: This study was conducted to determine whether paeoniflorin (PF) could prevent
H2O2-induced oxidative stress in ARPE-19 cells and to elucidate the molecular pathways …