Background In accordance with its mandate to provide guidance to Member States on health
policy matters, WHO issues a series of regularly updated position papers on vaccines and …

Background Public-health aspects Pertussis (whooping cough) is an important cause of
death in infants worldwide, and continues to be a publichealth concern even in countries …

The papers are reviewed by external experts and WHO staff, and reviewed and endorsed by
the WHO Strategic Advisory Group of Experts on immunization (SAGE)(http://www. who …

Background Pertussis has substantially increased in Quebec, Canada, since 1990. We
estimated pertussis vaccine effectiveness and vaccine coverage in child-care centers and …

Pertussis (whooping cough) remains an epidemic disease responsible for infant and child
morbidity and mortality, and is perceived as a serious public health problem. Since the …

Pertussis is a vaccine-preventable disease that causes morbidity and mortality, particularly
in infants and children< 5 years of age. The Global Pertussis Initiative (GPI) …

In the evaluation of vaccines, it can briefly be said that efficacy trials ask the question of how
a vaccine works in well-controlled settings, while effectiveness studies, on the other hand, try …

Universal pertussis vaccination continues to prevent a previously common and serious
disease of childhood. Despite widespread gains in disease control, pertussis has not been …

Abstract The Global Pertussis Initiative is an expert scientific forum that publishes consensus
recommendations concerning pertussis for many regions of the world. Here, we give …

Background. Acellular pertussis (aP) and whole-cell (wP) pertussis vaccines are presumed
to have similar short-term (< 3 years after completion of the primary series) efficacy …