Whole-genome analysis of diverse Chlamydia trachomatis strains identifies phylogenetic relationships masked by current clinical typing

SR Harris, IN Clarke, HMB Seth-Smith, AW Solomon… - Nature …, 2012 - nature.com
Chlamydia trachomatis is responsible for both trachoma and sexually transmitted infections,
causing substantial morbidity and economic cost globally. Despite this, our knowledge of its …

Population Genomics of Chlamydia trachomatis: Insights on Drift, Selection, Recombination, and Population Structure

SJ Joseph, X Didelot, J Rothschild… - Molecular biology …, 2012 - academic.oup.com
The large number of sexually transmitted diseases and ocular trachoma cases that are
caused globally each year by Chlamydia trachomatis has made this organism a World …

[HTML][HTML] Predicting phenotype and emerging strains among Chlamydia trachomatis infections

D Dean, WJ Bruno, R Wan, JP Gomes… - Emerging infectious …, 2009 - ncbi.nlm.nih.gov
Chlamydia trachomatis is a global cause of blinding trachoma and sexually transmitted
infections (STIs). We used comparative genomics of the family Chlamydiaceae to select …

Chlamydia trachomatis: genome sequence analysis of lymphogranuloma venereum isolates

NR Thomson, MTG Holden, C Carder… - Genome …, 2008 - genome.cshlp.org
Chlamydia trachomatis is the most common cause of sexually transmitted infections in the
UK, a statistic that is also reflected globally. There are three biovariants of C. trachomatis …

Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion

J Hadfield, SR Harris, HMB Seth-Smith… - Genome …, 2017 - genome.cshlp.org
Chlamydia trachomatis is the world's most prevalent bacterial sexually transmitted infection
and leading infectious cause of blindness, yet it is one of the least understood human …

[HTML][HTML] Interplay of recombination and selection in the genomes of Chlamydia trachomatis

SJ Joseph, X Didelot, K Gandhi, D Dean, TD Read - Biology direct, 2011 - Springer
Background Chlamydia trachomatis is an obligate intracellular bacterial parasite, which
causes several severe and debilitating diseases in humans. This study uses comparative …

[HTML][HTML] Whole-genome enrichment and sequencing of Chlamydia trachomatisdirectly from clinical samples

MT Christiansen, AC Brown, S Kundu, HJ Tutill… - BMC infectious …, 2014 - Springer
Background Chlamydia trachomatis is a pathogen of worldwide importance, causing more
than 100 million cases of sexually transmitted infections annually. Whole-genome …

Evolution of Chlamydia trachomatis diversity occurs by widespread interstrain recombination involving hotspots

JP Gomes, WJ Bruno, A Nunes, N Santos… - Genome …, 2007 - genome.cshlp.org
Chlamydia trachomatis is an obligate intracellular bacterium of major public health
significance, infecting over one-tenth of the world's population and causing blindness and …

Hypervirulent Chlamydia trachomatis Clinical Strain Is a Recombinant between Lymphogranuloma Venereum (L2) and D Lineages

N Somboonna, R Wan, DM Ojcius, MA Pettengill… - MBio, 2011 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular bacterium that causes a diversity of
severe and debilitating diseases worldwide. Sporadic and ongoing outbreaks of …

[HTML][HTML] Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain

HMB Seth-Smith, SR Harris, K Persson, P Marsh… - BMC genomics, 2009 - Springer
Background Chlamydia trachomatis is the most common cause of sexually transmitted
infections globally and the leading cause of preventable blindness in the developing world …