Sensory hair cells in the cochlea transduce environmental sounds into driven high-fidelity
neural signals that are conveyed by auditory nerve fibers to structures in the central auditory …

There are three times as many outer hair cells (OHC) as inner hair cells (IHC), yet IHC
transmit virtually all acoustic information to the brain as they synapse with 90–95% of type I …

Many, or most, tinnitus models rely on increased central gain in the auditory pathway as all
or part of the explanation, in that central auditory neurones deprived of their usual sensory …

Tinnitus, reduced sound-level tolerance, and difficulties hearing in noisy environments are
the most common complaints associated with sensorineural hearing loss in adult …

Naturally occurring stimuli can vary over several orders of magnitude and may exceed the
dynamic range of sensory neurons. As a result, sensory systems adapt their sensitivity by …

The prevalence of hearing problems in the Western world has, due to aging of the
population, doubled over the past 30 years. Thereby, noise-induced hearing loss is an …

Loudness is the primary perceptual correlate of sound intensity. The relationship between
sound intensity and loudness is not fixed, and can be modified by short-term sound …

Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural
activity transmitted from the cochlea to the central auditory system. Despite a reduced …

For many forms of sensorineural hearing loss, permanent threshold elevations are often
associated with hair cell damage or loss. These losses have received much experimental …

The exquisite sensitivity of the human ear to sound depends on the proper function of
mechanosensory hair cells that transduce mechanical stimuli into electrical signals. Sound …