Despite the extensive efforts of scientists, the genetic background of diabetic nephropathy
(DN) has not yet been clarified. To elucidate the genetic variants that predispose to the …

A critical challenge faced by clinical nephrologists today is the escalating number of patients
developing end stage renal disease, a major proportion of which is attributed to diabetic …

Aims/hypothesis This meta-analysis assessed the pooled effect of each genetic variant
reproducibly associated with diabetic nephropathy. Methods PubMed, EMBASE and Web of …

Diabetic nephropathy is a complex disease, caused by both environmental and genetic
factors. As in most complex diseases, genetic association studies in diabetic nephropathy …

Genetic aspects of diabetic nephropathy. Background Diabetic nephropathy from type 2
diabetes mellitus is the most common cause of end-stage renal disease (ESRD) in the …

Diabetic nephropathy (DN) is a devastating complication of type 1 and type 2 diabetes and
leads to increased morbidity and premature mortality. Susceptibility to DN has an inherent …

Clinical observations and epidemiological studies have shown that there is familial
aggregation of diabetic nephropathy in many ethnic groups, indicating the strong …

New genome-wide approaches offer new opportunities to identify genes associated with
diabetic nephropathy. However, such approaches have key limitations. Upto the present …

Diabetic nephropathy is the most common cause of end-stage renal disease in the Western
world. There is evidence for a genetic susceptibility to diabetic kidney disease, but despite …

Type 2 diabetic nephropathy is the most common cause of end-stage renal disease in
western Europe and the United States. Although patients with overt nephropathy generally …