Dissociation of immune determinants of outer membrane proteins of Chlamydia psittaci strain guinea pig inclusion conjunctivitis

TD Westbay, CC Dascher, RC Hsia… - Infection and …, 1994 - Am Soc Microbiol
Chlamydia trachomatis is an important human pathogen. Research to develop a Chlamydia
vaccine has focused on the major outer membrane protein (MOMP). Determinants of this …

Chlamydia muridarum T cell antigens and adjuvants that induce protective immunity in mice

H Yu, KP Karunakaran, X Jiang, C Shen… - Infection and …, 2012 - Am Soc Microbiol
Major impediments to a Chlamydia vaccine lie in discovering T cell antigens and polarizing
adjuvants that stimulate protective immunity. We previously reported the discovery of three T …

Novel Chlamydia muridarum T cell antigens induce protective immunity against lung and genital tract infection in murine models

H Yu, X Jiang, C Shen, KP Karunakaran… - The Journal of …, 2009 - journals.aai.org
Using a combination of affinity chromatography and tandem mass spectrometry, we recently
identified 8 MHC class II (IA b)-bound Chlamydia peptides eluted from dendritic cells (DCs) …

Immunization with an acellular vaccine consisting of the outer membrane complex of Chlamydia trachomatis induces protection against a genital challenge

S Pal, I Theodor, EM Peterson… - Infection and …, 1997 - Am Soc Microbiol
The ability to induce protection against a genital challenge was studied in BALB/c female
mice with three Chlamydia trachomatis mouse pneumonitis (MoPn) major outer membrane …

Immune specificity of murine T-cell lines to the major outer membrane protein of Chlamydia trachomatis

M Ishizaki, JE Allen, PR Beatty… - Infection and …, 1992 - Am Soc Microbiol
The antigenically variant Chlamydia trachomatis major outer membrane protein (MOMP) is a
target of antibody-mediated neutralization in vitro, and it is an important protein for designing …

Chlamydial polymorphic membrane proteins: regulation, function and potential vaccine candidates

S Vasilevsky, M Stojanov, G Greub, D Baud - Virulence, 2016 - Taylor & Francis
Pmps (Polymorphic Membrane Proteins) are a group of membrane bound surface exposed
chlamydial proteins that have been characterized as autotransporter adhesins and are …

[HTML][HTML] A Peptide Containing T-Cell Epitopes of Chlamydia trachomatis Recombinant MOMP Induces Systemic and Mucosal Antibody Responses in Mice

T Murtada A, S Shree R, H Kara, P Shreekumar R… - World journal of …, 2011 - scirp.org
We reported that intranasal immunization of mice with recombinant major outer membrane
protein (MOMP) of Chlamydia trachomatis genetically fused with modified cholera toxin …

Protective monoclonal antibodies to Chlamydia trachomatis serovar-and serogroup-specific major outer membrane protein determinants

YX Zhang, SJ Stewart, HD Caldwell - Infection and immunity, 1989 - Am Soc Microbiol
Monoclonal antibodies exhibiting Chlamydia trachomatis serovar specificity (serovar A, B-
Ba, or C) and serogroup specificity (B, intermediate, or C serogroup) were produced and …

Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission-blocking …

L Kari, WM Whitmire, DD Crane… - The Journal of …, 2009 - journals.aai.org
A vaccine is likely the most effective strategy for controlling human chlamydial infections.
Recent studies have shown immunization with Chlamydia muridarum major outer …

[HTML][HTML] A vaccine formulated with a combination of TLR-2 and TLR-9 adjuvants and the recombinant major outer membrane protein elicits a robust immune response …

C Cheng, S Pal, D Tifrea, Z Jia, LM de la Maza - Microbes and infection, 2014 - Elsevier
Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen in the
World and there is a need for a vaccine. To enhance the immunogenicity of a vaccine …