Chlamydia trachomatis is the most frequent sexually-transmitted disease-causing bacterium.
Urogenital serovars of this intracellular pathogen lead to urethritis and cervicitis. Ascending …

Chlamydia trachomatis is the most important infectious cause of infertility in women with
important implications in public health and for which a vaccine is urgently needed. Recent …

An important consideration for antichlamydial vaccine development is the induction of cross-
serovar protection, since multiple serovars (D to L) of Chlamydia trachomatis cause genital …

Despite intensive research on chlamydial pathogenesis and host immune responses,
vaccine development has been hampered by incomplete understanding of the virulence …

Three monoclonal antibodies (MAbs), E4, L1-4, and L1-24, to the major outer membrane
protein (MOMP) of Chlamydia trachomatis were identified that neutralized in vitro the …

Chlamydia trachomatis serovars DK are one of the most frequent causes of sexually
transmitted infections of the female genital tract, with possible complications such as …

To determine the ability of the major outer membrane protein (MOMP) to elicit cross-serovar
protection, groups of mice were immunized by the intramuscular (im) and subcutaneous (sc) …

To search for subunit vaccine candidates, immunogenic chlamydial antigens identified in
humans were evaluated for protection against both infection and pathology in a mouse …

The present study was undertaken to test the efficacy of immunization with the native major
outer membrane protein (nMOMP) of Chlamydia trachomatis mouse pneumonitis (MoPn) …

A common antigenic determinant on the chlamydial major outer membrane protein was
detected on each of the three Chlamydia trachomatis biovars (trachoma, lymphogranuloma …