Background and Purpose—Acute intracerebral hemorrhage (ICH) is a common and severe
form of stroke. To date, medical management of ICH has had scant impact on morbidity and …

Human Albumin is a unique pleiotropic protein with multiple properties. Previous clinical and
laboratory studies have indicated a possible beneficial effect of Albumin in subarachnoid …

Background and Purpose—We examined the neuroprotective efficacy of moderate-dose
human albumin therapy in acute focal ischemic stroke and defined the therapeutic window …

Preclinical studies have recently shown that albumin has neuroprotective effects for stroke in
animal models. Thus, we sought to evaluate the effects of albumin therapy in patients with …

In recent experimental studies, we demonstrated a highly beneficial neuroprotective effect of
moderate-to high-dose human albumin treatment of transient focal cerebral ischemia, but we …

Background and Purpose—High-dose human albumin (ALB) is robustly neuroprotective in
rodent stroke models. A phase I dose-escalation study was conducted to assess the safety of …

We characterized acute intracerebral hemorrhage (ICH) in the rat by sequential magnetic
resonance imaging (MRI) and correlated MRI findings with neurobehavior and …

Objective: Subarachnoid hemorrhage results in significant long-lasting neurologic sequelae.
Here, we investigated whether human albumin improves long-term outcomes in …

Background and Purpose—In preclinical stroke models, high-dose human albumin confers
robust neuroprotection. We investigated the safety and tolerability of this therapy in patients …

Background and Purpose—Human albumin has been shown to exert neuroprotective effects
in animal models of cerebral ischemia and humans with various intracranial pathologies. We …