Myocardial ischemia may occur as a result of pathophysiological and therapeutical
applications such as atherosclerosis, thromboembolism, percutaneous transluminal …

We determined the effects of olmesartan on infarct size and cardiac function in a rat
ischemia/reperfusion model. Rats underwent 30 min of left coronary artery (CA) occlusion …

The renin–angiotensin system (RAS) plays a major role in regulating the cardiovascular
system, and disorders of the RAS contribute largely to the cardiac pathophysiology …

We investigated the protective effect of angiotensin II (Ang II) type 1 receptor antagonist on
myocardial ischemia-reperfusion injury and the role of exogenous Ang II to this injury in …

Our study aimed to determine the effects of losartan and PD123319 in ischemia–reperfusion
(IR) injury in isolated perfused rat heart. The study used 40 male Wistar albino rats that were …

Angiotensin II (Ang II) and apoptosis contribute significantly to myocardial ischemia-
reperfusion (IH) in-jury. Evidence indicates that Ang Il may activate apoptosis in myocytes …

Background: We have previously shown that angiotensin II type 1 receptor blockers induce
cardioprotection and upregulate angiotensin II type 2 receptor during in vivo …

Cardiac remodeling after myocardial infarction is associated with impaired ventricular
function and heart failure and has important implications for survival. The purpose of the …

The angiotensin II type 1 receptor (AT1R) antagonist protects the heart against acute
ischaemia-reperfusion injury. The underlying mechanism is unclear. To determine the eff …

Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II type 1 (AT1) receptor
blockers improve ischemia–reperfusion induced arrhythmias and infarct size in several …