Folate deficiency during pregnancy has been related to low birth weight, preterm (PT) birth
and other health risks in the offspring; however, it is unknown whether prematurity is related …

Background Adequate folate levels are essential for successful pregnancy outcomes. We
aimed to study the relationship between placental mRNA and protein levels of folate …

Introduction Folates are essential nutrients for fetal development and pregnancy outcomes;
they are transported to the fetus during gestation through specific folate transporters located …

Background Folate plays a fundamental role for fetal development, participating in cell
division, embryogenesis, and fetal growth. The fetus depends on maternal supply of folate …

Folate is an essential micronutrient during pregnancy. The differential expression of genes
related to folate transport and metabolism during the advancing gestation and pregnancy …

The transport of folate across the placenta involves a number of different receptors including
folate receptor-alpha (FR-α), reduced folate carrier (RFC) and proton coupled folate …

The aim of this study was to elucidate the mechanism of folate transport in the placenta over
the course of pregnancy. We found that folate receptor α (FRα) and reduced folate carrier …

Folate deficiency in pregnancy is associated with neural tube defects, restricted fetal growth
and fetal programming of diseases later in life. Fetal folate availability is dependent on …

It is well understood that maternal folate deficiency can cause abnormal fetal development.
However, the extent to which placental development and function are also dependent upon …

Obese women have an approximately twofold higher risk to deliver an infant with neural
tube defects (NTDs) despite folate supplementation. Placental transfer of folate is mediated …