Draining lymph node (LN) enlargement has long been recognized as a hallmark of joint
inflammation in rheumatoid arthritis (RA) and can be quantified with magnetic resonance …

Rheumatoid arthritis is a chronic inflammatory disease manifested by episodic flares in
affected joints that are challenging to predict and treat. Longitudinal contrast enhanced-MRI …

Background/Purpose: Factors precipitating joint flare in rheumatoid arthritis (RA) patients are
poorly understood. Contrast enhanced (CE) MRI studies in murine models have identified …

Proliferation of draining lymphatic vessels coupled with dynamic changes in lymph node
volume and flow are characteristic features in rheumatoid arthritis (RA). Furthermore …

Objective To develop longitudinal 3‐dimensional (3‐D) measures of outcomes of
inflammation and bone erosion in murine arthritis using contrast‐enhanced magnetic …

Introduction A pivotal effect of lymphatic vessel (LV) function in joint homeostasis was
identified in the tumor necrosis factor-transgenic (TNF-Tg) mouse model of rheumatoid …

While erosion and tissue necrosis are the end‐stage result of inflammatory arthritis, factors
that can predict their initiation and severity are unknown. In an effort to identify these …

Rheumatoid arthritis (RA) is a chronic autoimmune disease with episodic flares in affected
joints; the etiology of RA is largely unknown. Recent studies in mice demonstrated that …

Background A major limitation of mouse models of arthritis is the absence of a quantitative,
longitudinal and translational outcome measure. Pre-clinical studies remain overly …

Background Emerging research on the mechanisms of disease chronicity in experimental
arthritis has included a new focus on the draining lymph node (LN). Here, we combined …