The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent
of life-threatening infections in immunocompromised subjects. A unique characteristic of …

The fungus Cryptococcus neoformans has emerged as a major cause of
meningoencephalitis worldwide. Host response to the fungus involves both innate and …

Cryptococcus neoformans is an opportunistic pathogen and the leading cause of fungal
meningitis in humans. Infection occurs following inhalation of C. neoformans cells, which, in …

Amino acid biosynthetic pathways that are absent in mammals are considered an attractive
target for antifungal therapy. Leucine biosynthesis is one such target pathway, consisting of …

Cryptococcus neoformans is a fungal pathogen that kills almost 200,000 people each year
and is distinguished by abundant and unique surface glycan structures that are rich in …

RATIONALE: Cryptococcus neoformans (Cn) is a globally distributed basidiomycetous yeast
and the predominant etiologic agent of human pulmonary and cerebral cryptococcosis. Host …

Polysaccharide capsules surround many fungal pathogens and contribute to virulence by
inhibiting complement-mediated phagocytosis. By purifying polysaccharide capsule …

The Rim101/PacC transcription factor acts in a fungal-specific signaling pathway
responsible for sensing extracellular pH signals. First characterized in ascomycete fungi …

Cryptococcus neoformans is an environmental pathogen requiring atmospheric levels of
oxygen for optimal growth. Upon inhalation, C. neoformans disseminates to the brain and …

Transcriptional Regulatory Map of Iron Homeostasis Reveals a New Control Circuit for
Capsule Formation in Cryptococcus neoformans | Genetics | Oxford Academic Skip to Main …