[HTML][HTML] Curcumin improves cardiopulmonary resuscitation outcomes by modulating mitochondrial metabolism and apoptosis in a rat model of cardiac arrest

J Zhang, S Liu, L Jiang, J Hou, Z Yang - Frontiers in cardiovascular …, 2022 - frontiersin.org
Background Curcumin, a diarylheptanoid chemical compound extracted from curcuma
longa, exerts a variety of biological and pharmacological effects in numerous pathological …

Curcumin ameliorates cardiac dysfunction induced by mechanical trauma

X Li, T Cao, S Ma, Z Jing, Y Bi, J Zhou, C Chen… - European Journal of …, 2017 - Elsevier
Curcumin, a phytochemical component derived from turmeric (Carcuma longa), has been
extensively investigated because of its anti-inflammatory and anti-oxidative properties …

[HTML][HTML] Curcumin simultaneously improves mitochondrial dynamics and myocardial cell bioenergy after sepsis via the SIRT1-DRP1/PGC-1α pathway

D Hou, H Liao, S Hao, R Liu, H Huang, C Duan - Heliyon, 2024 - cell.com
Septic cardiomyopathy (SCM) is associated with an imbalance in mitochondrial quality and
high mortality rates, with no effective treatment developed to date. Curcumin provides …

Cardio-protective effect of tetrahydrocurcumin, the primary hydrogenated metabolite of curcumin in vivo and in vitro: Induction of apoptosis and autophagy via PI3K …

X Chen, Q Xie, Y Zhu, J Xu, G Lin, S Liu, Z Su… - European Journal of …, 2021 - Elsevier
Tetrahydrocurcumin (THC) is an essential metabolite of curcumin, a major active component
of the Curcuma species, which have been used traditionally for the treatment of …

[HTML][HTML] Tetrahydrocurcumin ameliorates postinfarction cardiac dysfunction and remodeling by inhibiting oxidative stress and preserving mitochondrial function via …

B Zhang, J Yang, X Li, H Zhu, J Sun, L Jiang, C Xue… - Phytomedicine, 2023 - Elsevier
Background Myocardial infarction (MI) often leads to sudden cardiac death. Persistent
myocardial ischemia increases oxidative stress and impairs mitochondrial function …

[HTML][HTML] Curcumin attenuates myocardial ischemia–reperfusion injury

K Liu, H Chen, QS You, Q Ye, F Wang, S Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Background Cardiovascular diseases (CVDs) are at a badly high-risk of morbidity and
mortality in the world. Methods Our study was attempted to investigate the cardioprotective …

[HTML][HTML] Myocardial ischemia reperfusion injury is alleviated by curcumin-peptide hydrogel via upregulating autophagy and protecting mitochondrial function

CL Liao, Y Liu, MZ Huang, HY Liu, ZL Ye… - Stem Cell Research & …, 2021 - Springer
Background Ischemia-reperfusion injury (IRI) is an important factor limiting the success of
cardiac reperfusion therapy. Curcumin has a significant cardioprotective effect against IRI …

[HTML][HTML] Cardioprotective effect of curcumin on myocardial ischemia/reperfusion injury: a meta-analysis of preclinical animal studies

YF Zeng, QH Guo, XY Wei, SY Chen, S Deng… - Frontiers in …, 2023 - frontiersin.org
Objective: This meta-analysis aimed to determine the efficacy of curcumin in preventing
myocardial ischemia/reperfusion (I/R) injury in animal models. Methods: Studies published …

Curcumin induces the apoptotic intrinsic pathway via upregulation of reactive oxygen species and JNKs in H9c2 cardiac myoblasts

K Zikaki, IK Aggeli, C Gaitanaki, I Beis - Apoptosis, 2014 - Springer
Curcumin derived from the rhizome of turmeric (Curcuma longa L.), is a well known coloring
culinary agent, that has therapeutic properties against diverse pathologies such as cancer …

Curcumin as a potential protective compound against cardiac diseases

S Jiang, J Han, T Li, Z Xin, Z Ma, W Di, W Hu… - Pharmacological …, 2017 - Elsevier
Curcumin, which was first used 3000 years ago as an anti-inflammatory agent, is a well-
known bioactive compound derived from the active ingredient of turmeric (Curcuma longa) …