Therapeutic trials in difficult to treat steroid sensitive nephrotic syndrome: challenges and future directions

AM McKay, RS Parekh, D Noone - Pediatric Nephrology, 2023 - Springer
Steroid sensitive nephrotic syndrome is a common condition in pediatric nephrology, and
most children have excellent outcomes. Yet, 50% of children will require steroid-sparing …

[HTML][HTML] New lessons from randomized trials in steroid-sensitive nephrotic syndrome: clear evidence against long steroid therapy

PF Hoyer - Kidney international, 2015 - Elsevier
The best initial therapy for steroid-sensitive nephrotic syndrome (SSNS) in children is
subject to ongoing debate. Systematic reviews and meta-analyses have concluded that at …

Update on the treatment of steroid-sensitive nephrotic syndrome

F Zotta, M Vivarelli, F Emma - Pediatric nephrology, 2022 - Springer
Steroid-sensitive nephrotic syndrome (SSNS) is a rare condition that develops primarily in
preadolescent children after the age of 1 year. Since the 1950s, oral corticosteroids have …

Evaluation and management of steroid-sensitive nephrotic syndrome

EM Hodson, SI Alexander - Current opinion in pediatrics, 2008 - journals.lww.com
Progress has been made towards elucidating the cause of steroid-sensitive nephrotic
syndrome. Data from adequately powered randomized controlled trials are still required to …

Current understandings in treating children with steroid-resistant nephrotic syndrome

JM Lee, A Kronbichler, JI Shin, J Oh - Pediatric Nephrology, 2021 - Springer
Steroid-resistant nephrotic syndrome (SRNS) remains a challenge for paediatric
nephrologists. SRNS is viewed as a heterogeneous disease entity including immune-based …

Evidence-based management of steroid-sensitive nephrotic syndrome

EM Hodson, JC Craig, NS Willis - Pediatric Nephrology, 2005 - Springer
Using data from systematic reviews and randomised controlled trials, the evidence for
managing steroid sensitive nephrotic syndrome (SSNS) is reviewed. In the initial episode …

Treatment of steroid-sensitive nephrotic syndrome: new guidelines from KDIGO

RM Lombel, DS Gipson, EM Hodson - Pediatric nephrology, 2013 - Springer
Abstract The 2012 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice
guideline on glomerulonephritis (GN) is intended to assist the practitioner caring for patients …

IPNA clinical practice recommendations for the diagnosis and management of children with steroid-sensitive nephrotic syndrome

A Trautmann, O Boyer, E Hodson, A Bagga… - Pediatric …, 2023 - Springer
Idiopathic nephrotic syndrome is the most frequent pediatric glomerular disease, affecting
from 1.15 to 16.9 per 100,000 children per year globally. It is characterized by massive …

Interventions for steroid-resistant nephrotic syndrome: a systematic review

D Habashy, EM Hodson, JC Craig - Pediatric nephrology, 2003 - Springer
In a systematic review and meta-analysis of randomized controlled trials (RCT), we aimed to
evaluate the benefits and harms of all interventions for children with steroid-resistant …

Pediatric idiopathic steroid-sensitive nephrotic syndrome: diagnosis and therapy—short version of the updated German best practice guideline (S2e)—AWMF register …

R Ehren, MR Benz, PT Brinkkötter, J Dötsch… - Pediatric …, 2021 - Springer
Idiopathic nephrotic syndrome is the most frequent glomerular disease in children in most
parts of the world. Children with steroid-sensitive nephrotic syndrome (SSNS) generally …