Vascular cognitive impairment, dementia, aging and energy demand. A vicious cycle
A Popa-Wagner, AM Buga, B Popescu… - Journal of neural …, 2015 - Springer
To a great extent, cognitive health depends on cerebrovascular health and a deeper
understanding of the subtle interactions between cerebrovascular function and cognition is …
understanding of the subtle interactions between cerebrovascular function and cognition is …
[HTML][HTML] Neurovascular dysfunction in vascular dementia, Alzheimer's and atherosclerosis
Efficient blood supply to the brain is of paramount importance to its normal functioning and
improper blood flow can result in potentially devastating neurological consequences …
improper blood flow can result in potentially devastating neurological consequences …
The overlap between neurodegenerative and vascular factors in the pathogenesis of dementia
C Iadecola - Acta neuropathologica, 2010 - Springer
There is increasing evidence that cerebrovascular dysfunction plays a role not only in
vascular causes of cognitive impairment but also in Alzheimer's disease (AD). Vascular risk …
vascular causes of cognitive impairment but also in Alzheimer's disease (AD). Vascular risk …
The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged
S Craft - Archives of neurology, 2009 - jamanetwork.com
In recent years a rapidly increasing number of studies has focused on the relationship
between dementia and metabolic disorders such as diabetes, obesity, hypertension, and …
between dementia and metabolic disorders such as diabetes, obesity, hypertension, and …
[HTML][HTML] The role of insulin in the vascular contributions to age-related dementia
TM Hughes, S Craft - Biochimica et Biophysica Acta (BBA)-Molecular Basis …, 2016 - Elsevier
In addition to its well-known role in energy metabolism in the body, insulin is a vasoactive
hormone that regulates peripheral and cerebral blood flow and neuronal function. Vascular …
hormone that regulates peripheral and cerebral blood flow and neuronal function. Vascular …
Neurovascular unit dysregulation, white matter disease, and executive dysfunction: the shared triad of vascular cognitive impairment and Alzheimer disease
Executive dysfunction is the most important predictor for loss of independence in dementia.
As executive function involves the coordination of distributed cerebral functions, executive …
As executive function involves the coordination of distributed cerebral functions, executive …
Contribution of cerebral microvascular mechanisms to age-related cognitive impairment and dementia
X Fang, RF Crumpler, KN Thomas… - Physiology …, 2022 - akjournals.com
Cognitive impairment and dementia are significant health burdens worldwide. Aging,
hypertension, and diabetes are the primary risk factors for Alzheimer's disease and …
hypertension, and diabetes are the primary risk factors for Alzheimer's disease and …
Age‐related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review
The process of aging includes changes in cellular biology that affect local interactions
between cells and their environments and eventually propagate to systemic levels. In the …
between cells and their environments and eventually propagate to systemic levels. In the …
Vascular contribution to cognition in stroke and Alzheimer's disease
Y Yang, J Fuh, VCT Mok - Brain Science Advances, 2018 - journals.sagepub.com
Vascular factors to cognitive impairment in degenerative on non-degenerative diseases
have been reported, examined, and debated for several decades. The various definitions of …
have been reported, examined, and debated for several decades. The various definitions of …
Cerebral microvascular pathology in aging and Alzheimer's disease
E Farkas, PGM Luiten - Progress in neurobiology, 2001 - Elsevier
The aging of the central nervous system and the development of incapacitating neurological
diseases like Alzheimer's disease (AD) are generally associated with a wide range of …
diseases like Alzheimer's disease (AD) are generally associated with a wide range of …