Toxic nephropathies

JF Maher - Therapy of Renal Diseases and Related Disorders, 1991 - Springer
Recently, toxic nephropathy has emerged as an important segment of clinical renal disease.
The high prevealence of nephrotoxic lesions reflects increased human exposure to a wide …

[PDF][PDF] Urinary biomarkers to detect significant effects of environmental and occupational exposure to nephrotoxins. II. Nephrotoxins of significant frequency and …

R Goyer, G Eknoyan, ME De Broe, VM Buckalew… - Renal …, 1997 - Taylor & Francis
The social and economic impact of renal disease worldwide is considerable. In the United
States, the number of new patients requiring treatment approximates 40,000 per year. It …

Clinical relevance

GA Porter - Clinical nephrotoxins: Renal injury from drugs and …, 2008 - Springer
Drugs are a frequent cause of both in-hospital and community-acquired acute kidney injury
(AKI). Nephrotoxic drugs share the spotlight with renal hypoxia as primary etiologic factors …

Nephrotoxic exposures and acute kidney injury in noncritically ill children stratified by service

PE Holsteen, KM Gist, JT Brinton, M Hebert… - Hospital …, 2022 - publications.aap.org
OBJECTIVE The Nephrotoxic Injury Negated by Just-in-Time Action (NINJA) program is a
multicenter, quality improvement initiative that identifies patients at risk for nephrotoxic …

Clinical relevance and predictive value of damage biomarkers of drug-induced kidney injury

SL Kane-Gill, PL Smithburger, K Kashani, JA Kellum… - Drug safety, 2017 - Springer
Nephrotoxin exposure accounts for up to one-fourth of acute kidney injury episodes in
hospitalized patients, and the associated consequences are as severe as acute kidney …

[HTML][HTML] A sustained quality improvement program reduces nephrotoxic medication-associated acute kidney injury

SL Goldstein, T Mottes, K Simpson, C Barclay… - Kidney international, 2016 - Elsevier
Exposure to nephrotoxic medication is among the most common causes of acute kidney
injury (AKI) in hospitalized patients. Here we conducted a prospective quality improvement …

The developing kidney and environmental toxins

MJ Solhaug, PM Bolger, PA Jose - Pediatrics, 2004 - publications.aap.org
The effects of environmental chemicals, drugs, and physical agents on the developing
kidney are influenced by the state of renal development and maturation. The development of …

Mechanisms of antimicrobial-induced nephrotoxicity in children

KJ Downes, M Hayes, JC Fitzgerald… - Journal of …, 2020 - academic.oup.com
Drug-induced nephrotoxicity is responsible for 20% to 60% of cases of acute kidney injury in
hospitalized patients and is associated with increased morbidity and mortality in both …

Nephrotoxic medications and acute kidney injury risk factors in the neonatal intensive care unit: clinical challenges for neonatologists and nephrologists

HJ Murphy, B Thomas, B Van Wyk, SB Tierney… - Pediatric …, 2020 - Springer
Neonatal acute kidney injury (AKI) is common. Critically ill neonates are at risk for AKI for
many reasons including the severity of their underlying illnesses, prematurity, and …

Non-drug-induced nephrotoxicity

J Bacchetta, L Dubourg, L Juillard, P Cochat - Pediatric Nephrology, 2009 - Springer
Several drugs and other compounds can induce acute and/or chronic nephrotoxicity. The
goal of this study was to review clinical features of nephrotoxicity induced by 'atypical'or …