Pharmacological Management of Acute Spinal Cord Injury: Overlooked Opportunities to Enhance Long-Term Neurological Function

C Jutzeler, B Tong, E Bailey, NY Harel… - Available at SSRN …, 2019 - papers.ssrn.com
Background: Complications arising from acute traumatic spinal cord injury are routinely
managed by various pharmacological interventions. Despite decades of clinical application …

North American clinical trials network for the treatment of spinal cord injury: goals and progress

RG Grossman, EG Toups, RF Frankowski… - … of Neurosurgery: Spine, 2012 - thejns.org
The North American Clinical Trials Network (NACTN) for the Treatment of Spinal Cord Injury
is a consortium of 10 neurosurgery departments, a data management center, and a …

Pharmacologic treatment and surgical timing for spinal cord injury

AR Vaccaro, K Singh - Current Opinion in Orthopaedics, 1999 - journals.lww.com
There is considerable debate regarding the optimal acute treatment of spinal cord injuries.
The main issues include the selection of efficacious pharmacologic agents designed to …

Acute spinal cord injury, part I: pathophysiologic mechanisms

RJ Dumont, DO Okonkwo, S Verma… - Clinical …, 2001 - journals.lww.com
Spinal cord injury (SCI) is a devastating and common neurologic disorder that has profound
influences on modern society from physical, psychosocial, and socioeconomic perspectives …

New perspectives for the treatment options in spinal cord injury

HS Sharma - Expert Opinion on Pharmacotherapy, 2008 - Taylor & Francis
Spinal cord injury (SCI) is a serious clinical disorder that leads to lifetime disability for which
no suitable therapeutic agents are available so far. Further research is needed to …

New pharmacologic approaches to acute spinal cord injury

DH Rhoney, MS Luer, M Hughes… - … : The Journal of Human …, 1996 - Wiley Online Library
The incidence of spinal cord injury (SCI) in the United States is approximately 10,000 new
cases per year. Strategies to prevent injury or salvage a few dermatomal levels may have …

Pharmacological and nonpharmacological therapeutic strategies based on the pathophysiology of acute and chronic spinal cord injury

E Garcia, R Rodríguez-Barrera… - Essentials of spinal …, 2018 - books.google.com
Spinal cord injury (SCI) induces a series of anatomic and physiological disorders which
have severe repercussions on neural function. SCI is classified chronologically into an acute …

The effectiveness of surgery on the treatment of acute spinal cord injury and its relation to pharmacological treatment

MS Duh, MJ Shepard, JE Wilberger, MB Bracken - Neurosurgery, 1994 - journals.lww.com
Abstract USING DATA FROM the Second National Acute Spinal Cord Injury Study (NASCIS
II), the authors sought to characterize the role of surgery in the management of traumatic …

[PDF][PDF] Pathophysiological mechanisms involved in systemic and metabolic alterations secondary to spinal cord injury

G Guízar-Sahagún… - PROCEEDINGS …, 1998 - researchgate.net
Spinal cord injury (SCI) has captured the interest of different scientific and social disciplines,
as such injury in humans represents medical and socioeconomic problems of great …

Rapid quantification of tissue damage for assessing acute spinal cord injury therapy

W Young - Journal of neurotrauma, 1992 - liebertpub.com
Therecently published results of the National Acute Spinal Cord Injury Study (NASCIS II)
have complicated studies of acute spinal cord injury treatments in several ways. First …