Clinical trials in spinal cord injury

CH Tator, MG Fehlings - Blue Books of Practical Neurology, 2001 - Elsevier
Publisher Summary This chapter provides a review of the clinical evidence for the value of
pharmacotherapy and other measures, such as surgical decompression for the treatment of …

Pharmacologic treatment of neuropathic pain following spinal cord injury

S DeFrates, AM Cook - Orthopedics, 2011 - journals.healio.com
Approximately 11,000 people will experience a spinal cord injury in the United States each
year, with over half of those between the ages of 16 and 30 years. An estimated 183,000 to …

[PDF][PDF] Pathophysiology of the spinal cord injury.

T Yılmaz, Y Turan, A Keleş - Journal of Clinical & Experimental …, 2014 - jceionline.org
Spinal cord injury (SCI) causes significant morbidity and mortality leading to serious social
problems. Although many studies conducted on it, any universal treatment protocol has not …

Rapid quantification of tissue damage for assessing acute spinal cord injury therapy

W Young - Journal of neurotrauma, 1992 - liebertpub.com
Therecently published results of the National Acute Spinal Cord Injury Study (NASCIS II)
have complicated studies of acute spinal cord injury treatments in several ways. First …

Spinal cord injuries and repairs: research progress and prospects

Z Huang, Y Liu - Chinese Journal of Pharmacology and …, 2017 - pesquisa.bvsalud.org
Therapeutic intervention and rehabilitation after spinal cord injury (SCI) are currently
confronted with tremendous challenges in basic and clinical medicine. The pathological …

Pharmacological therapy of spinal cord injury during the acute phase

V Pointillart, ME Petitjean, L Wiart, JM Vital, P Lassié… - Spinal cord, 2000 - nature.com
Objectives: To evaluate the safety and effect on neurological outcome of nimodipine,
methylprednisolone, or both versus no medical treatment in spinal-cord injury during the …

Recent advances in the management of spinal cord injury.

GF Morris, LF Marshall - Western Journal of Medicine, 1997 - ncbi.nlm.nih.gov
414 WIMP June 1997-Vol 166, No. 6 Epitomes-Neurosurgery ond noncontiguous fracture
exists. Screening evaluation of the entire axis from occiput to sacrum is necessary and …

Spinal cord injury pharmacotherapy: Current research & development and competitive commercial landscape as of 2015

JR Guercio, JE Kralic, EJ Marrotte… - The Journal of Spinal …, 2019 - Taylor & Francis
Context Current treatment of spinal cord injury (SCI) focuses on cord stabilization to prevent
further injury, rehabilitation, management of non-motor symptoms, and prevention of …

[PDF][PDF] Pharmacological neuroprotective therapy for acute spinal cord injury: state of the art

S Martinon, A Ibarra - Mini Reviews in Medicinal Chemistry, 2008 - academia.edu
Pharmacological Neuroprotective Therapy for Acute Spinal Cord Injury: State of the Art Page 1
222 Mini-Reviews in Medicinal Chemistry, 2008, 8, 222-230 1389-5575/08 $55.00+.00 © 2008 …

Acute spinal cord injury: pharmacotherapy and drug development perspectives.

AR Blight, MP Zimber - Current opinion in investigational drugs …, 2001 - europepmc.org
There are no drugs specifically approved for spinal cord injury that directly address the
underlying damage to neural tissue. Immediate treatment with methylprednisolone sodium …