Limiting spinal cord injury by pharmacological intervention

JV Priestley, AT Michael-Titus, W Tetzlaff - Handbook of clinical neurology, 2012 - Elsevier
The direct primary mechanical trauma to neurons, glia and blood vessels that occurs with
spinal cord injury (SCI) is followed by a complex cascade of biochemical and cellular …

Medication before and after a spinal cord lesion

EK Jensen, F Biering-Sørensen - Spinal Cord, 2014 - nature.com
Objective: To map the impact of spinal cord lesion (SCL) on medication. Study design:
Registration of medication for 72 patients before SCL and at discharge from the Department …

Pharmacological neuroprotection for acute spinal cord injury

H Mestre, R Balanza, A Ibarra - Recent Advances in Medicinal Chemistry, 2014 - Elsevier
Traumatic spinal cord injury (SCI) is a major problem in clinical medicine. Etiology depends
on several factors such as mechanism of injury and level of injury. The result is a very …

[HTML][HTML] Spinal cord injury—past, present, and future

WH Donovan - The Journal of Spinal Cord Medicine, 2007 - ncbi.nlm.nih.gov
This special report traces the path of spinal cord injury (SCI) from ancient times through the
present and provides an optimistic overview of promising clinical trials and avenues of basic …

[HTML][HTML] Spinal cord injury prevalence and treatment modalities

Z Ara, A Singh, S Raj, S Walliullah… - Spinal Cord Injury …, 2023 - intechopen.com
Spinal cord injury (SCI) is a devasting neurological condition producing physical
dependency, morbidity, psychological stress, and financial burden. During the last 30 years …

Acute spinal cord injury: A review of pathophysiology and potential of non-steroidal anti-inflammatory drugs for pharmacological intervention

E Hayta, H Elden - Journal of Chemical Neuroanatomy, 2018 - Elsevier
Acute spinal cord injury (SCI) is one of the serious central nervous system injuries, which
can lead to significant neurological impairments and a reduction in quality of life with loss in …

Management of cervical spinal cord trauma.

VK Sonntag, RA Douglas - Journal of neurotrauma, 1992 - europepmc.org
Trauma victims with cervical spinal cord injuries should be managed by proper
immobilization and immediate reduction of spinal cord fractures to anatomical alignment …

Levels of spinal cord injury and predictors of neurologic recovery

SC Kirshblum, KC O'Connor - … medicine and rehabilitation clinics of North …, 2000 - Elsevier
A comprehensive physical examination of the patient with acute spinal cord injury is
essential in determining the initial level of injury and is the most accurate method of …

Recent advances in pathophysiology and treatment of spinal cord injury

CE Hulsebosch - Advances in physiology education, 2002 - journals.physiology.org
Thirty years ago, patients with spinal cord injury (SCI) and their families were told “nothing
can be done” to improve function. Since the SCI patient population is reaching normal life …

Pharmacological treatment of acute, experimental spinal cord injury

DK Anderson - Neural monitoring: the prevention of intraoperative …, 1990 - Springer
Various pharmacologic agents have been reported to be effective in the treatment of acute
experimental spinal cord injury. Their mechanism (s) of action is problematic. However …