Cell-penetrating peptides (CPPs) have emerged as powerful tools in terms of drug delivery.
Those short, often cationic peptides are characterized by their usually low toxicity and their …

Drug delivery systems are generally believed to comprise drugs and excipients. A peptide–
drug conjugate is a single molecule that can simultaneously play multiple roles in a drug …

Most toxic agents currently used for chemotherapy show a narrow therapeutic window,
because of their inability to distinguish between healthy and cancer cells. Targeted drug …

Targeted delivery of chemotherapeutics and diagnostic agents conjugated to carrier ligands
has made significant progress in recent years, both in regards to the structural design of the …

Targeted drug delivery to specific group of cells offers an attractive strategy to minimize the
undesirable side effects and achieve the therapeutic effect with a lower dose. Both linear …

Background: Integrins are heterodimeric cell surface receptors that mediate cell-cell and cell-
extracellular matrix adhesion. These molecules play a role in processes such as cell growth …

Cancer is the second leading cause of death affecting nearly one in two people, and the
appearance of new cases is projected to rise by> 70% by 2030. To effectively combat the …

Cell-penetrating peptides (CPP) are promising tools for the transport of a broad range of
compounds into cells. Since the discovery of the first members of this peptide family, many …

Cell penetrating peptides (CPPs) have received substantial attention due to their intrinsic
property to cross plasma membranes or even as helpers to facilitate the cellular entry of drug …

During the last decade, the potential of peptides for drug delivery into cells has been
highlighted by the discovery of several cell-penetrating peptides (CPPs). CPPs are very …