Sex hormones regulate lipid metabolism in adult Sertoli cells: A genome-wide study of estrogen and androgen receptor binding sites
Optimal functioning of Sertoli cells is crucial for spermatogenesis which is under tight
regulation of sex hormones, estrogen and androgen. Adult rat Sertoli cells expresses …
regulation of sex hormones, estrogen and androgen. Adult rat Sertoli cells expresses …
Genome-wide identification of estrogen receptor binding sites reveals novel estrogen-responsive pathways in adult male germ cells
S Raut, AV Kumar, K Khambata… - Biochemical …, 2020 - portlandpress.com
Spermatogenesis occurs in the seminiferous epithelium that shows the presence of estrogen
receptors alpha (ERα) and beta (ERβ), both of which regulate gene transcription by binding …
receptors alpha (ERα) and beta (ERβ), both of which regulate gene transcription by binding …
Research resource: the dynamic transcriptional profile of sertoli cells during the progression of spermatogenesis
Sertoli cells (SCs), the only somatic cells within seminiferous tubules, associate intimately
with developing germ cells. They not only provide physical and nutritional support but also …
with developing germ cells. They not only provide physical and nutritional support but also …
Characterization of cholesterol metabolism in Sertoli cells and spermatogenesis
JF Shi, YK Li, K Ren, YJ Xie… - Molecular medicine …, 2018 - spandidos-publications.com
The Sertoli cell, which is the supporting cell of spermatogenesis, has an important role in the
endocrine and paracrine control of spermatogenesis. Functionally, it provides the cells of the …
endocrine and paracrine control of spermatogenesis. Functionally, it provides the cells of the …
New insights on hormones and factors that modulate Sertoli cell metabolism
Sertoli cells (SCs) play a key role in spermatogenesis by providing the physical support for
developing germ cells and ensuring them the appropriate nutrients, energy sources …
developing germ cells and ensuring them the appropriate nutrients, energy sources …
Molecular mechanisms and signaling pathways involved in the nutritional support of spermatogenesis by Sertoli cells
Sertoli cells play a central role in spermatogenesis. They maintain the blood-testis barrier,
an essential feature of seminiferous tubules which creates the proper environment for the …
an essential feature of seminiferous tubules which creates the proper environment for the …
Do estrogens regulate lipid status in testicular steroidogenic Leydig cell?
A Milon, M Kaczmarczyk, P Pawlicki, B Bilinska… - Acta histochemica, 2019 - Elsevier
In this study mouse Leydig cell (MA-10) were treated with G-protein coupled membrane
estrogen receptor antagonist (G-15; 10 nM). Cells were analyzed by Western blotting for …
estrogen receptor antagonist (G-15; 10 nM). Cells were analyzed by Western blotting for …
Hormonal control of Sertoli cell metabolism regulates spermatogenesis
Hormonal regulation is essential to spermatogenesis. Sertoli cells (SCs) have functions that
reach far beyond the physical support of germ cells, as they are responsible for creating the …
reach far beyond the physical support of germ cells, as they are responsible for creating the …
[HTML][HTML] Single-cell RNA sequencing defines the regulation of spermatogenesis by Sertoli-cell androgen signaling
C Cao, Q Ma, S Mo, G Shu, Q Liu, J Ye… - Frontiers in Cell and …, 2021 - frontiersin.org
Androgen receptor (AR) signaling is essential for maintaining spermatogenesis and male
fertility. However, the molecular mechanisms by which AR acts between male germ cells …
fertility. However, the molecular mechanisms by which AR acts between male germ cells …
Lipid metabolism is closely associated with normal testicular growth based on global transcriptome profiles in normal and underdeveloped testis of obese zucker (fa/fa …
J Datar, A Regassa, WK Kim, CG Taylor, P Zahradka… - Lipids, 2017 - Springer
Zucker (fa/fa) obese rats often have non-identical and differently sized paired testes, leaving
one testis underdeveloped. Our earlier study found that the underdeveloped testes,> 30 …
one testis underdeveloped. Our earlier study found that the underdeveloped testes,> 30 …