Background: Frontal asymmetry plays a major role in depression. However, patients with
treatment-resistant depression (TRD) have widespread hypofrontality. We investigated …

Background Previous functional neuroimaging studies of depression have demonstrated
frontotemporal dysfunction, including the dorsolateral prefrontal cortex, while patients …

Background Psychomotor retardation (PMR) is frequently noted as a characteristic feature of
major depressive disorder (MDD). In patients with depression, it is characterized by …

Aim: Functional neuroimaging studies to date have indicated prefrontal dysfunction in late‐
onset major depression (LOD). The relationships between prefrontal dysfunction and clinical …

BACKGROUND: Although recent neuroimaging and therapeutic transcranial magnetic
cortex stimulation (TMS) studies suggest imbalance between left and right dorsolateral …

Objective The study investigated cognitive performance and brain function between
treatment-resistant depression (TRD) and non-TRD patients to find potential neurobiological …

Multi-channel near-infrared spectroscopy (NIRS) is a noninvasive, on-the-spot, functional
neuroimaging technique allowing detection of the spatiotemporal characteristics of brain …

Background Anxious depression is a serious mental disorder characterized by comorbidity
of anxiety and depression, and its symptoms are similar to those of non-anxious depression …

Background Bipolar depression (BD) is a unique, severe and prevalent mental illness that
shares many similarities in symptoms with unipolar depression (UD). Improving precision of …

Background Major depressive disorder (MDD) is often resistant to treatment with usual
approaches. Patients with MDD have shown hypofunction of the frontotemporal cortex in …