Carbamazepine adverse drug reactions

I Fricke-Galindo, A LLerena, H Jung-Cook… - Expert review of …, 2018 - Taylor & Francis
Introduction: Carbamazepine (CBZ) is used for the treatment of epilepsy and other
neurological and psychiatric disorders. The occurrence of adverse reactions (ADRs) to CBZ …

[HTML][HTML] Carbamazepine toxicity

Y Al Khalili, S Sekhon, S Jain - StatPearls [Internet], 2023 - ncbi.nlm.nih.gov
Objectives: Outline the toxicokinetics and pathophysiology of carbamazepine toxicity.
Identify the presentation of a patient with carbamazepine toxicity, and potential differential …

Associations of HLA genetic variants with carbamazepine‐induced cutaneous adverse drug reactions: An updated meta‐analysis

M Biswas, M Ershadian, J Shobana… - Clinical and …, 2022 - Wiley Online Library
Aggregated risk of carbamazepine (CBZ)‐induced cutaneous adverse drug reactions
(cADRs) with different HLA variants are unclear and limited in terms of the power of studies …

PharmGKB summary: carbamazepine pathway

CF Thorn, SG Leckband, J Kelsoe… - Pharmacogenetics …, 2011 - journals.lww.com
Carbamazepine (CBZ), a dibenzazepine, is a tricyclic compound used in the treatment of
epilepsy, trigeminal neuralgia, and psychiatric mood disorders [1]. Serious adverse events …

Shared genetic risk factors across carbamazepine‐induced hypersensitivity reactions

P Nicoletti, S Barrett, L McEvoy, AK Daly… - Clinical …, 2019 - Wiley Online Library
Carbamazepine (CBZ) causes life‐threating T‐cell‐mediated hypersensitivity reactions,
including serious cutaneous adverse reactions (SCAR s) and drug‐induced liver injury (CBZ …

Carbamazepine side effects in children and adults

JM Pellock - Epilepsia, 1987 - Wiley Online Library
Most of the side effects associated with carbamazepine (Tegretol®, USP, Geigy
Pharmaceuticals) therapy are mild, transient, and reversible with an adjustment in dosage or …

HLA alleles and hypersensitivity to carbamazepine: an updated systematic review with meta-analysis

S Grover, R Kukreti - Pharmacogenetics and genomics, 2014 - journals.lww.com
Objective A considerable heterogeneity exists in the literature on the role of different HLA
alleles in carbamazepine (CBZ)-induced cutaneous adverse drug reactions (cADRs) of …

Recommendations for HLA‐B* 15: 02 and HLA‐A* 31: 01 genetic testing to reduce the risk of carbamazepine‐induced hypersensitivity reactions

U Amstutz, NH Shear, MJ Rieder, S Hwang, V Fung… - …, 2014 - Wiley Online Library
Objective To systematically review evidence on genetic risk factors for carbamazepine (CBZ)–
induced hypersensitivity reactions (HSR s) and provide practice recommendations …

Clinically significant pharmacokinetic drug interactions with carbamazepine: an update

E Spina, F Pisani, E Perucca - Clinical pharmacokinetics, 1996 - Springer
Carbamazepine is one of the most commonly prescribed antiepileptic drugs and is also
used in the treatment of trigeminal neuralgia and psychiatric disorders, particularly bipolar …

Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions

SI Hung, WH Chung, SH Jee, WC Chen… - Pharmacogenetics …, 2006 - journals.lww.com
The anticonvulsant carbamazepine (CBZ) frequently causes cutaneous adverse drug
reactions (cADRs), including maculopapular eruption (MPE), hypersensitivity syndrome …