Neuroinflammation plays a critical role in the process of neurodegenerative disorders,
during which microglia, the principal resident immune cells in the central nervous system …

Purpose: Sepsis-associated encephalopathy (SAE) induces cognitive dysfunction via
mechanisms that commonly involve neuroinflammation. Yin Yang 1 (YY1) is an important …

Aim Clinical and preclinical studies suggest that alterations in the peripheral and brain
immune system are associated with the pathophysiology of depression, also leading to …

Neuropathic pain is induced by primary injury and dysfunction of the nervous system, and is
accompanied by the activation of inflammation signaling pathways. Yin Yang 1 (YY1) is …

Previous studies have revealed a critical role of YY1, a “Yin Yang” transcription factor, in
cancer development and progression. However, whether YY1 has any role in rheumatoid …

Activated microglia in the retina are essential for the development of autoimmune uveitis. Yin‐
Yang 1 (YY1) is an important transcription factor that participates in multiple inflammatory …

Background and purpose: An inflammatory response in the central nervous system
mediated by the activation of microglia is a key event in the early stages of the development …

Abstract The transcription factor Yin Yang 1 (YY1) is ubiquitously expressed in mammalian
cells, regulating the expression of a variety of genes involved in proliferation, differentiation …

The N6-methyladenosine (m6A) modification is the most abundant posttranscriptional
mRNA modification in mammalian cells and is dynamically modulated by a series of …

Abstract Yin yang 2 (YY2) is a multifunctional zinc finger protein that belongs to the yin yang
(YY) family. YY2 has dual function in regulating gene expression, as it could act either as a …