Magnesium sulfate and fetal neuroprotection: overview of clinical evidence

C Chollat, S Marret - Neural regeneration research, 2018 - journals.lww.com
Antenatal administration of magnesium sulfate is an important part of the neuroprotective
strategy for preterm infants. Strong evidence from five randomized controlled trials and five …

Fetal neuroprotection by magnesium sulfate: from translational research to clinical application

C Chollat, L Sentilhes, S Marret - Frontiers in neurology, 2018 - frontiersin.org
Despite improvements in perinatal care, preterm birth still occurs regularly and the
associated brain injury and adverse neurological outcomes remain a persistent challenge …

Antenatal magnesium sulfate: neuro-protection for preterm infants

S Oddie, DJ Tuffnell, W McGuire - … of Disease in Childhood-Fetal and …, 2015 - fn.bmj.com
The neuro-protective effect of antenatal magnesium sulfate on very preterm infants has been
demonstrated in good-quality randomised controlled trials and meta-analyses. Magnesium …

Effects of antenatal exposure to magnesium sulfate on neuroprotection and mortality in preterm infants: a meta-analysis

MM Costantine, SJ Weiner… - Obstetrics & …, 2009 - journals.lww.com
METHODS OF STUDY SELECTION: Randomized controlled trials comparing magnesium
sulfate with placebo/other treatment in patients at risk of preterm delivery were evaluated for …

Magnesium sulphate at 30 to 34 weeks' gestational age: neuroprotection trial (MAGENTA)-study protocol

CA Crowther, PF Middleton, D Wilkinson… - BMC pregnancy and …, 2013 - Springer
Background Magnesium sulphate is currently recommended for neuroprotection of preterm
infants for women at risk of preterm birth at less than 30 weeks' gestation, based on high …

Antenatal magnesium sulfate for fetal neuroprotection: a critical appraisal and systematic review of clinical practice guidelines

PM Jayaram, MK Mohan, I Farid… - Journal of perinatal …, 2019 - degruyter.com
Background Magnesium sulfate is an accepted intervention for fetal neuroprotection. There
are some perceived differences in the international recommendations on the use …

Protection of brain development by antenatal magnesium sulphate for infants born preterm

C Chollat, L Sentilhes, S Marret - Developmental Medicine & …, 2019 - Wiley Online Library
Cerebral palsy (CP) remains the most significant neurological disorder associated with
preterm birth. It disrupts quality of life and places huge cost burdens on society. Antenatal …

Assessing the neuroprotective benefits for babies of antenatal magnesium sulphate: an individual participant data meta-analysis

CA Crowther, PF Middleton, M Voysey, L Askie… - PLoS …, 2017 - journals.plos.org
Background Babies born preterm are at an increased risk of dying in the first weeks of life,
and those who survive have a higher rate of cerebral palsy (CP) compared with babies born …

Magnesium sulphate for fetal neuroprotection at imminent risk for preterm delivery: a systematic review with meta‐analysis and trial sequential analysis

HT Wolf, LD Huusom, TB Henriksen… - … journal of obstetrics …, 2020 - Wiley Online Library
Background Ordinary meta‐analyses indicate that magnesium sulphate (MgSO4) treatment
in women at imminent risk for preterm delivery decreases the offspring's risk of cerebral …

No. 376-magnesium sulphate for fetal neuroprotection

LA Magee, DA De Silva, D Sawchuck, A Synnes… - Journal of Obstetrics and …, 2019 - Elsevier
Objective The objective is to provide guidelines for the use of antenatal magnesium sulphate
for fetal neuroprotection of the preterm infant. Options Antenatal magnesium sulphate …