Hyaluronan in tissue injury and repair
A hallmark of tissue injury and repair is the turnover of extracellular matrix components. This
review focuses on the role of the glycosaminoglycan hyaluronan in tissue injury and repair …
review focuses on the role of the glycosaminoglycan hyaluronan in tissue injury and repair …
Hyaluronan as an immune regulator in human diseases
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue
injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety …
injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety …
Matrix regulation of lung injury, inflammation, and repair: the role of innate immunity
PW Noble, D Jiang - Proceedings of the American Thoracic Society, 2006 - atsjournals.org
Mechanisms that regulate host defense after noninfectious tissue injury are incompletely
understood. Our laboratory is interested in the role of the extracellular matrix …
understood. Our laboratory is interested in the role of the extracellular matrix …
Regulation of lung injury and repair by Toll-like receptors and hyaluronan
Mechanisms that regulate inflammation and repair after acute lung injury are incompletely
understood. The extracellular matrix glycosaminoglycan hyaluronan is produced after tissue …
understood. The extracellular matrix glycosaminoglycan hyaluronan is produced after tissue …
Hyaluronan as a therapeutic target in human diseases
Accumulation and turnover of extracellular matrix is a hallmark of tissue injury, repair and
remodeling in human diseases. Hyaluronan is a major component of the extracellular matrix …
remodeling in human diseases. Hyaluronan is a major component of the extracellular matrix …
Hyaluronan and its catabolic products in tissue injury and repair
PW Noble - Matrix biology, 2002 - Elsevier
Hyaluronan is an unbiquitous glycosaminoglycan present in most tissues. Under
homeostatic conditions hyaluronan exists as a high molecular mass polymer that has …
homeostatic conditions hyaluronan exists as a high molecular mass polymer that has …
Hyaluronan in wound healing: rediscovering a major player
KL Aya, R Stern - Wound repair and regeneration, 2014 - Wiley Online Library
Wound healing involves a series of carefully modulated steps, from initial injury and blood
clot to the final reconstituted tissue or scar. A dynamic reciprocity exists throughout between …
clot to the final reconstituted tissue or scar. A dynamic reciprocity exists throughout between …
Functions of hyaluronan in wound repair
WYJ Chen - Hyaluronan, 2002 - Elsevier
Hyaluronan (HA), a major extracellular matrix macromolecule, has a repeated disaccharide
structure that is completely conserved throughout a large span of evolution, indicating a …
structure that is completely conserved throughout a large span of evolution, indicating a …
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2
KR Taylor, K Yamasaki, KA Radek, A Di Nardo… - Journal of Biological …, 2007 - ASBMB
Inflammation under sterile conditions is not well understood despite its importance in trauma
and autoimmune disease. To investigate this process we established mouse models of …
and autoimmune disease. To investigate this process we established mouse models of …
Hyaluronan
A Almond - Cellular and Molecular Life Sciences, 2007 - Springer
The polysaccharide hyaluronan is an essential component of the vertebrate extracellular
matrix and also produced by viruses, bacteria and fungi. Although the hyaluronan polymer is …
matrix and also produced by viruses, bacteria and fungi. Although the hyaluronan polymer is …