Melanins, the main pigments of the skin and hair in mammals, are synthesized within
membrane-bound organelles of melanocytes called melanosomes. Melanosome structure …

The major focus of this article is on mammalian skin pigmentation, including the regulation of
pigment production, and the biogenesis of melanosomes and their intracellular and …

Melanosomes are lysosome‐related organelles within which melanin pigments are
synthesized and stored in melanocytes and retinal pigment epithelial cells. Early …

Vertebrate pigment cells in the eye and skin are useful models for cell types that use
specialized endosomal trafficking pathways to partition cargo proteins to unique lysosome …

Melanosomes are tissue-specific lysosome-related organelles of pigment cells in which
melanins are synthesized and stored. Analyses of the trafficking and fate of melanosomal …

Melanogenesis is the unique process of producing pigmented biopolymers that are
sequestered within melanosomes, which provides color to the skin, hair and eyes of animals …

Melanin pigments are responsible for human skin and hair color, and they protect the body
from harmful ultraviolet light. The black and brown melanin pigments are synthesized in …

Melanosomes are morphologically and functionally unique organelles within which melanin
pigments are synthesized and stored. Melanosomes share some characteristics with …

Melanosomes are the specialized intracellular organelles of pigment cells devoted to the
synthesis, storage and transport of melanin pigments, which are responsible for most visible …

Pigmentation not only provides a wide range of cosmetic coloration to the skin, hair and
eyes, but also provides the underlying tissue significant protection from ultraviolet (UV) …