[PDF][PDF] Understanding the Structural and Functional Correlates of Acute Lung Inflammation in Two Murine Models

M Kaur - 2022 - harvest.usask.ca
The outcome of lung inflammation is important to host survival as lungs are necessary for
oxygen exchange and fighting pathogens or any injurious stimuli. Thus, diagnosing and …

Quantification of regional murine ozone-induced lung inflammation using [18F]F-FDG microPET/CT imaging

GK Aulakh, M Kaur, V Brown, S Ekanayake, B Khan… - Scientific Reports, 2020 - nature.com
Ozone (O3) is a highly potent and reactive air pollutant. It has been linked to acute and
chronic respiratory diseases in humans by inducing inflammation. Our studies have found …

2-deoxy-2-[18F]fluoro-D-glucose Positron Emission Tomography to Monitor Lung Inflammation and Therapeutic Response to Dexamethasone in a Murine Model of …

PZ Mannes, CE Barnes, JD Latoche, KE Day… - Molecular Imaging and …, 2023 - Springer
Purpose To image inflammation and monitor therapeutic response to anti-inflammatory
intervention using 2-deoxy-2-[18F] fluoro-D-glucose ([18F] FDG) positron emission …

Visualizing lung cellular adaptations during combined ozone and LPS induced murine acute lung injury

JAB Duda, M Kaur, GK Aulakh - JoVE (Journal of Visualized Experiments), 2021 - jove.com
Lungs are continually faced with direct and indirect insults in the form of sterile (particles or
reactive toxins) and infectious (bacterial, viral or fungal) inflammatory conditions. An …

Spatial heterogeneity of lung strain and aeration and regional inflammation during early lung injury assessed with PET/CT

G Motta-Ribeiro, T Winkler, S Hashimoto, MFV Melo - Academic radiology, 2019 - Elsevier
Introduction Spatial heterogeneity of lung aeration and strain (change volume/resting
volume) occurs at microscopic levels and contributes to lung injury. Yet, it is mostly assessed …

18F-fluoro-2-deoxyglucose PET informs neutrophil accumulation and activation in lipopolysaccharide-induced acute lung injury

RS Rodrigues, FA Bozza, CJ Hanrahan… - Nuclear medicine and …, 2017 - Elsevier
Introduction Molecular imaging of the earliest events related to the development of acute
lung injury (ALI)/acute respiratory distress syndrome (ARDS) could facilitate therapeutic …

A Lipopolysaccharide (LPS) inhalation model to characterise divergent innate cellular responses and presence of alveolar leak, early in the course of acute lung …

S Wiscombe - 2021 - theses.ncl.ac.uk
Acute respiratory distress syndrome (ARDS) is a common condition presenting to the
intensive care unit (ICU) and is associated with high morbidity and mortality. Experimental …

Molecular imaging of inflammation with PET in acute and ventilator-induced lung injury

G Musch - Frontiers in Physiology, 2023 - frontiersin.org
This review focuses on methods to image acute lung inflammation with Positron Emission
Tomography (PET). Four approaches are discussed that differ for biologic function of the …

Mechanistic understanding of lung inflammation: recent advances and emerging techniques

C Keskinidou, AG Vassiliou, I Dimopoulou… - Journal of …, 2022 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is a life-threatening lung injury characterized by
an acute inflammatory response in the lung parenchyma. Hence, it is considered as the most …

Strain differences in alveolar neutrophil infiltration and macrophage phenotypes in an acute lung inflammation model

Y Zhang, X Lin, K Koga, K Takahashi, HM Linge… - Molecular …, 2011 - Springer
Pulmonary infection is a major cause of mortality and morbidity, and the magnitude of the
lung inflammatory response correlates with patient survival. Previously, we have shown that …