The 40-Hz White Light-Emitting Diode (LED) improves the structure–function of the brain mitochondrial KATP channel and respiratory chain activities in amyloid beta …

M Nazari, T Vajed-Samiei, N Torabi… - Molecular …, 2022 - Springer
It has been described that using noninvasive exposure to 40-Hz white light LED reduces
amyloid-beta, a peptide thought to initiate neurotoxic events in Alzheimer's disease (AD) …

The Effect of 40-Hz White LED Therapy on Structure–Function of Brain Mitochondrial ATP-Sensitive Ca-Activated Large-Conductance Potassium Channel in Amyloid …

M Nazari, A Jafari, N Torabi, T Vajed-Samiei… - Neurotoxicity …, 2022 - Springer
Photobiomodulation therapy has become the focus of medical research in many areas such
as Alzheimer's disease (AD), because of its modulatory effect on cellular processes through …

Near-infrared light reduces β-amyloid-stimulated microglial toxicity and enhances survival of neurons: Mechanisms of light therapy for Alzheimer's disease

YV Stepanov, I Golovynska, R Zhang… - Alzheimer's research & …, 2022 - Springer
Background Low-intensity light can decelerate neurodegenerative disease progression and
reduce amyloid β (Aβ) levels in the cortex, though the cellular and molecular mechanisms by …

Low-level laser therapy for beta amyloid toxicity in rat hippocampus

Y Lu, R Wang, Y Dong, D Tucker, N Zhao… - Neurobiology of …, 2017 - Elsevier
Beta amyloid (Aβ) is well accepted to play a central role in the pathogenesis of Alzheimer's
disease (AD). The present work evaluated the therapeutic effects of low-level laser …

Intromitochondrial IκB/NF-κB signaling pathway is involved in amyloid β peptide-induced mitochondrial dysfunction

C Shi, XM Zhu, J Wang, D Long - Journal of bioenergetics and …, 2014 - Springer
Mitochondrial dysfunction is a hallmark of amyloid β peptide (Aβ)-induced neuronal toxicity
in Alzheimer's disease (AD). However, the underlying mechanism (s) of Aβ-induced …

Attenuation Aβ1-42-induced neurotoxicity in neuronal cell by 660nm and 810nm LED light irradiation

S Thammasart, P Namchaiw, K Pasuwat… - PLoS …, 2023 - journals.plos.org
Oligomeric amyloid-β 1–42 (Aβ1–42) has a close correlation with neurodegenerative
disorder especially Alzheimer's disease (AD). It induces oxidative stress and mitochondrial …

Targeting Microglial KATP Channels to Treat Neurodegenerative Diseases: A Mitochondrial Issue

MJ Rodríguez, M Martínez-Moreno… - Oxidative Medicine …, 2013 - Wiley Online Library
Neurodegeneration is a complex process involving different cell types and
neurotransmitters. A common characteristic of neurodegenerative disorders is the …

Melatonin protective effect against amyloid β-induced neurotoxicity mediated by mitochondrial biogenesis; involvement of hippocampal Sirtuin-1 signaling pathway

MA Dezfouli, M Zahmatkesh, M Farahmandfar… - Physiology & …, 2019 - Elsevier
Melatonin has a potential therapeutic value in Alzheimer's disease (AD), a disease that is
associated with a dramatic decline in memory and cognitive abilities. The aggregation of the …

The K ATP channel activator diazoxide ameliorates amyloid-β and Tau pathologies and improves memory in the 3xTgAD mouse model of Alzheimer's disease

D Liu, M Pitta, JH Lee, B Ray, DK Lahiri… - Journal of …, 2010 - content.iospress.com
Compromised cellular energy metabolism, cerebral hypoperfusion, and neuronal calcium
dysregulation are involved in the pathological process of Alzheimer's disease (AD). ATP …

Near-infrared light via light-emitting diode treatment is therapeutic against rotenone-and 1-methyl-4-phenylpyridinium ion-induced neurotoxicity

HL Liang, HT Whelan, JT Eells, MTT Wong-Riley - Neuroscience, 2008 - Elsevier
Parkinson's disease is a common progressive neurodegenerative disorder characterized by
the degeneration of dopaminergic neurons in the substantia nigra pars compacta …