Abstract Objective Imipenem-relebactam (IMR), a novel β-lactam/β-lactamase inhibitor
combination, is recommended for infections caused by difficult-to-treat Pseudomonas …

Multidrug resistance (MDR) represents a global threat to health. Although plasmids can play
an important role in the dissemination of MDR, they have not been commonly linked to the …

Pseudomonas aeruginosa is an important human pathogen and the leading cause of
nosocomial infections. P. aeruginosa is characterized by massive intrinsic resistance to a …

Pseudomonas aeruginosa is a major opportunistic human pathogen that causes nosocomial
infections, and the proportion of carbapenem resistance has recently dramatically increased …

Infections caused by carbapenem-resistant Pseudomonas aeruginosa strains represent a
major therapeutic and epidemiological problem. The aim of this study was to characterize …

Scope Pseudomonas aeruginosa, a ubiquitous opportunistic pathogen considered one of
the paradigms of antimicrobial resistance, is among the main causes of hospital-acquired …

Whole-genome sequencing (WGS) was used for the characterization of the frequently
extensively drug resistant (XDR) Pseudomonas aeruginosa sequence type 175 (ST175) …

Introduction: Emergence of carbapenem resistance in Pseudomonas aeruginosa increases
the therapeutic dilemma. In this study, we investigated various mechanisms involved in the …

Antibiotic resistance has become a serious threat to human health (WHO Antibacterial
Agents in Clinical Development: an Analysis of the Antibacterial Clinical Development …

Chronic lung infections due to the persistence of Pseudomonas aeruginosa in cystic fibrosis
patients are typically associated with the emergence of antibiotic resistance. The purpose of …