Tumor penetrating peptides for improved drug delivery
E Ruoslahti - Advanced drug delivery reviews, 2017 - Elsevier
In vivo screening of phage libraries in tumor-bearing mice has been used to identify
peptides that direct phage homing to a tumor. The power of in vivo phage screening is …
peptides that direct phage homing to a tumor. The power of in vivo phage screening is …
Applications of cell-penetrating peptides for tumor targeting and future cancer therapies
J Regberg, A Srimanee, Ü Langel - Pharmaceuticals, 2012 - mdpi.com
Cell-penetrating peptides provide a highly promising strategy for intracellular drug delivery.
One relevant clinical application of cell-penetrating peptides is cancer therapeutics. Peptide …
One relevant clinical application of cell-penetrating peptides is cancer therapeutics. Peptide …
Peptide and protein drug delivery to and into tumors: challenges and solutions
VP Torchilin, AN Lukyanov - Drug discovery today, 2003 - Elsevier
The potential of peptide and protein anticancer agents has yet to be realized owing to the
many unresolved problems concerning their delivery to the site of a tumor and into tumor …
many unresolved problems concerning their delivery to the site of a tumor and into tumor …
Tumor-penetrating peptides
T Teesalu, KN Sugahara, E Ruoslahti - Frontiers in oncology, 2013 - frontiersin.org
Tumor-homing peptides can be used to deliver drugs into tumors. Phage library screening in
live mice has recently identified homing peptides that specifically recognize the endothelium …
live mice has recently identified homing peptides that specifically recognize the endothelium …
Recent developments in anticancer drug delivery using cell penetrating and tumor targeting peptides
Efficient intracellular trafficking and targeted delivery to the site of action are essential to
overcome the current drawbacks of cancer therapeutics. Cell Penetrating Peptides (CPPs) …
overcome the current drawbacks of cancer therapeutics. Cell Penetrating Peptides (CPPs) …
Selective targeting of cancer cells using synthetic peptides
M Shadidi, M Sioud - Drug Resistance Updates, 2003 - Elsevier
To establish efficient and reliable therapeutic delivery into cancer cells, a number of delivery
agents and concepts have been investigated in the recent years. Among many …
agents and concepts have been investigated in the recent years. Among many …
Cell-penetrating peptides transport therapeutics into cells
JD Ramsey, NH Flynn - Pharmacology & therapeutics, 2015 - Elsevier
Nearly 30 years ago, certain small, relatively nontoxic peptides were discovered to be
capable of traversing the cell membrane. These cell-penetrating peptides, as they are now …
capable of traversing the cell membrane. These cell-penetrating peptides, as they are now …
[HTML][HTML] Cell penetrating peptides in preclinical and clinical cancer diagnosis and therapy
Delivery of imaging reagents and drugs to tumors is essential for cancer diagnosis and
therapy. In addition to therapeutic and diagnostic functionalities, peptides have potential …
therapy. In addition to therapeutic and diagnostic functionalities, peptides have potential …
Peptide-based targeted therapeutics: Focus on cancer treatment
Therapeutic peptides are attracting increasing attention for biomedical applications.
Peptides present promising opportunities in targeted drug delivery due to their high …
Peptides present promising opportunities in targeted drug delivery due to their high …
Enzyme-triggered, cell penetrating peptide-mediated delivery of anti-tumor agents
H He, L Sun, J Ye, E Liu, S Chen, Q Liang… - Journal of Controlled …, 2016 - Elsevier
Conventional chemotherapy has little or no specificity for cancer cells, normally resulting in
low drug accumulation at the tumor region (inefficacy) and drug-induced severe side effects …
low drug accumulation at the tumor region (inefficacy) and drug-induced severe side effects …