Abstract Between 2002 and 2004, the standardized 28-day protocol recently developed by
the World Health Organization was used to explore the efficacy of chloroquine, in the …

We conducted an efficacy study of chloroquine (CQ), sulfadoxine–pyrimethamine (SP) and a
combination of both (SP+ CQ) for the treatment of uncomplicated malaria in an area of low …

Background The World Health Organization recommends intermittent preventive treatment
in pregnancy (IPTp) with sulfadoxine‐pyrimethamine for malaria for all women who live in …

Background Randomized controlled clinical trials (RCTs) of adjunctive treatment to reduce
the high‐mortality associated with cerebral malaria (CM) have so far failed to show any …

Abstract Background. In 2008, Guinea-Bissau introduced artemether-lumefantrine for
treatment of uncomplicated malaria. Previously, 3 times the standard dose of chloroquine …

Sulfadoxine/pyrimethamine (SP) is increasingly used against malaria in sub-Saharan Africa
because of chloroquine resistance. However, chloroquine may have a beneficial antipyretic …

Background This study aimed to synthesize the existing evidence on the efficacy and safety
of a single dose artemisinin–naphthoquine (ASNQ) for treatment of uncomplicated malaria …

Background. Recent clinical trials in the Lao People's Democratic Republic have
demonstrated that chloroquine and sulfadoxine-pyrimethamine, which are national malaria …

Background An artemisinin-based combination therapy, artesunate (AS) plus sulphadoxine-
pyrimethamine (SP), was compared to SP monotherapy to provide evidence of further …

The efficacy and kinetics of the combination chloroquine plus sulfadoxine‐pyrimethamine
(CQ+ SP), given sequentially and simultaneously, were investigated in 32 patients with …