Primary aldosteronism is a severe form of autonomous aldosteronism. Milder forms of
autonomous and renin-independent aldosteronism may be common, even in normotension …

Background While both renin‐dependent and renin‐independent aldosterone secretion
contribute to aldosteronism, their relative associations with cardiovascular disease (CVD) …

Context: Mild cases of autonomous aldosterone secretion may go unrecognized using
current diagnostic criteria for primary aldosteronism (PA). Objective: To investigate whether …

Background: Primary aldosteronism is recognized as a severe form of renin-independent
aldosteronism that results in excessive mineralocorticoid receptor (MR) activation. Objective …

Background: Primary aldosteronism is a nonsuppressible renin-independent aldosterone
production that causes hypertension and cardiovascular disease. Objective: To characterize …

Since its initial description in 1955, primary aldosteronism was thought to be a rare cause of
hypertension. However, improved screening methods show that primary aldosteronism is a …

Context New approaches are needed to address the evolution of the primary aldosteronism
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …

Recent reports suggesting that the prevalence of primary hyperaldosteronism may be higher
than historically thought have relied on an elevated plasma aldosterone …

Primary aldosteronism, the most common secondary form of hypertension, is thought to be
present in≈ 5% to 10% of hypertensive adults. However, recent studies indicate that its …

Since its initial description in 1955, primary aldosteronism was thought to be a rare cause of
hypertension. However, with improved screening methodologies, it appears that primary …