Plasma aldosterone and renin levels have been associated with blood pressure increase
and 3–4 year incidence of hypertension in a middle-aged North American community in …

The idiom from Socrates,'the more we learn, the less we know', can be applied to
aldosterone with its different facets and its pleiotropic effects. There is clear evidence for …

Objective It is unknown why some patients with biochemical evidence of primary
aldosteronism (PA) do not develop hypertension. We aimed to compare clinical and …

The basic clinical pathophysiology of primary aldosteronism (PAL) was described by Conn
in terms of autonomous production of aldosterone, secondary suppression of renin and …

Primary aldosteronism is a frequent cause of resistant hypertension and is associated with
an increased risk of developing diabetes mellitus. Aldosterone impairs insulin secretion in …

Objective The prevalence of primary aldosteronism in unselected hypertensive patients is
currently unknown. We investigated the frequency of positive screening results for primary …

Objective: To review the first reported cases of successfully treated pheochromocytoma and
primary aldosteronism and document the diagnostic and therapeutic advances that have …

An increased plasma aldosterone concentration (PAC) with decreased plasma renin activity
(PRA) is the abnormal endocrine finding in primary aldosteronism (PA). However, it remains …

Background: Previous studies showed higher risk of cardiovascular and cerebrovascular
(CCV) events in primary aldosteronism compared with essential hypertension, but the …

A higher risk of cardiovascular events has been reported in patients with primary
aldosteronism (PA) than in otherwise similar patients with essential hypertension (EH) …