Therapeutic approach to low-grade serous ovarian carcinoma: state of art and perspectives of clinical research

A Gadducci, S Cosio - Cancers, 2020 - mdpi.com
Low-grade serous ovarian carcinoma (LGSOC) is a distinct pathologic and clinical entity,
characterized by less aggressive biological behavior, lower sensitivity to chemotherapy and …

Ovarian low-grade serous carcinoma: a comprehensive update

I Diaz-Padilla, AL Malpica, L Minig, LM Chiva… - Gynecologic …, 2012 - Elsevier
Ovarian low-grade serous ovarian carcinoma (OvLGSCa) comprises a minority within the
heterogeneous group of ovarian carcinomas. Despite biological differences with their high …

[HTML][HTML] Low grade serous ovarian cancer–a rare disease with increasing therapeutic options

TA Zwimpfer, O Tal, F Geissler, R Coelho… - Cancer Treatment …, 2023 - Elsevier
High-grade serous ovarian cancers (HGSOCs) most commonly arise from the fimbrial end of
the fallopian tube and harbor TP53 gene mutations. In contrast, low-grade serous ovarian …

New therapeutic opportunities for women with low-grade serous ovarian cancer

T Moujaber, RL Balleine, B Gao… - Endocrine-Related …, 2022 - erc.bioscientifica.com
Low-grade serous ovarian cancer (LGSC) is a morphologically and molecularly distinct
subtype of ovarian cancer, accounting for~ 10% of serous carcinomas. Women typically …

[HTML][HTML] Low-grade serous ovarian carcinoma

E Ricciardi, T Baert, B Ataseven, F Heitz… - Geburtshilfe und …, 2018 - thieme-connect.com
In the early 2000s a two-tier grading system was introduced for serous ovarian cancer. Since
then, we have increasingly come to accept that low-grade serous ovarian carcinoma …

Advanced low grade serous ovarian cancer: a retrospective analysis of surgical and chemotherapeutic management in two high volume oncological centers

P Di Lorenzo, V Conteduca, E Scarpi, M Adorni… - Frontiers in …, 2022 - frontiersin.org
Simple summary Low-grade serous ovarian cancer (LGSOC) represents an uncommon
histotype of serous ovarian cancer (accounting for approximately 5% of all ovarian cancer) …

Chemotherapy response in low‐grade serous ovarian carcinoma at a comprehensive cancer center: Readdressing the roles of platinum and cytotoxic therapies

BL Manning‐Geist, RM Kahn, D Nemirovsky… - Cancer, 2023 - Wiley Online Library
Background Data on platinum sensitivity of low‐grade serous ovarian carcinoma (LGSOC)
in the upfront setting is lacking, and there is limited and contradictory information on …

Low-grade serous carcinoma of the ovary: the current status

A Babaier, H Mal, W Alselwi, P Ghatage - Diagnostics, 2022 - mdpi.com
Low-grade serous carcinoma (LGSC) of the ovary is a rare histological subtype of epithelial
ovarian carcinoma. It has distinct clinical behavior and a specific molecular profile …

Primary cytoreductive surgery and adjuvant hormonal monotherapy in women with advanced low-grade serous ovarian carcinoma: Reducing overtreatment without …

AN Fader, J Bergstrom, A Jernigan, EJ Tanner III… - Gynecologic …, 2017 - Elsevier
Objectives Women with advanced-stage, low-grade serous ovarian carcinoma (LGSC) have
low chemotherapy response rates and poor overall survival. Most LGSC tumors overexpress …

Low-grade serous ovarian cancer: expert consensus report on the state of the science

RN Grisham, BM Slomovitz, N Andrews… - International Journal of …, 2023 - ijgc.bmj.com
Compared with high-grade serous carcinoma, low-grade serous carcinoma of the ovary or
peritoneum is a less frequent epithelial ovarian cancer type that is poorly sensitive to …