[HTML][HTML] Immunopharmacology of post-myocardial infarction and heart failure medications
The immune system responds to acute tissue damage after myocardial infarction (MI) and
orchestrates healing and recovery of the heart. However, excessive inflammation may lead …
orchestrates healing and recovery of the heart. However, excessive inflammation may lead …
Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition
Following a myocardial infarction (MI), the immune system helps to repair ischaemic
damage and restore tissue integrity, but excessive inflammation has been implicated in …
damage and restore tissue integrity, but excessive inflammation has been implicated in …
[HTML][HTML] Post-ischemic myocardial inflammatory response: a complex and dynamic process susceptible to immunomodulatory therapies
NJ Pluijmert, DE Atsma, PHA Quax - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Following acute occlusion of a coronary artery causing myocardial ischemia and
implementing first-line treatment involving rapid reperfusion, a dynamic and balanced …
implementing first-line treatment involving rapid reperfusion, a dynamic and balanced …
[HTML][HTML] Immune cells drive new immunomodulatory therapies for myocardial infarction: From basic to clinical translation
W Nian, Z Huang, C Fu - Frontiers in Immunology, 2023 - frontiersin.org
The high incidence of heart failure secondary to myocardial infarction (MI) has been difficult
to effectively address. MI causes strong aseptic inflammation, and infiltration of different …
to effectively address. MI causes strong aseptic inflammation, and infiltration of different …
Immunomodulation and immunopharmacology in heart failure
G Markousis-Mavrogenis, L Baumhove… - Nature Reviews …, 2024 - nature.com
The immune system is intimately involved in the pathophysiology of heart failure. However, it
is currently underused as a therapeutic target in the clinical setting. Moreover, the …
is currently underused as a therapeutic target in the clinical setting. Moreover, the …
Mechanisms of cardioprotection via modulation of the immune response
GA Grilo, PR Shaver, LE de Castro Brás - Current Opinion in Pharmacology, 2017 - Elsevier
Highlights•Current research focus on cardioprotective immune-targeted therapeutic
approaches.•Ischemic preconditioning is a powerful cardioprotective treatment.•The immune …
approaches.•Ischemic preconditioning is a powerful cardioprotective treatment.•The immune …
[HTML][HTML] The role of immune cells in cardiac remodeling after myocardial infarction
Y Zhang, W Wen, H Liu - Journal of cardiovascular pharmacology, 2020 - journals.lww.com
Myocardial infarction (MI) is an irreversible damage of the heart muscle, which often leads to
adverse cardiac remodeling and progressive heart failure. After MI, immune cells play a vital …
adverse cardiac remodeling and progressive heart failure. After MI, immune cells play a vital …
Autoimmunity in myocardial infarction
YH Liao, X Cheng - International journal of cardiology, 2006 - Elsevier
Myocardial infarction is associated with an immune response. Physiological inflammation
response causes self-repair and protection, while pathological autoimmune response leads …
response causes self-repair and protection, while pathological autoimmune response leads …
The cardiac injury immune response as a target for regenerative and cellular therapies
Purpose Despite modern reperfusion and pharmacologic therapies, myocardial infarction
(MI) remains a leading cause of morbidity and mortality worldwide. Therefore, the …
(MI) remains a leading cause of morbidity and mortality worldwide. Therefore, the …
[HTML][HTML] Innate immune receptors in heart failure: Side effect or potential therapeutic target?
KB Wagner, SB Felix, A Riad - World journal of cardiology, 2014 - ncbi.nlm.nih.gov
Heart failure (HF) is a leading cause of mortality and morbidity in western countries and
occasions major expenses for public health systems. Although optimal medical treatment is …
occasions major expenses for public health systems. Although optimal medical treatment is …