Obesity is reaching epidemic proportions globally and represents a major cause of
comorbidities, mostly related to cardiovascular disease. The autonomic nervous system …

Experimental evidence suggests a crucial role of the autonomic nervous system in whole
body metabolism with major regulatory effects of the parasympathetic branch in postprandial …

Obesity is a growing health problem worldwide with a major impact on health and
healthcare expenditures. Medical therapy in the form of diet and pharmacotherapy has …

Abdominal pain continues to be a major challenge and unmet need in clinical practice.
Normalization of bidirectional gut-brain signaling has generated much interest as a …

Current pharmacological and behavioral approaches to obesity face high dietary relapse
rates. Suboptimal outcomes have also been reported following bariatric surgery …

Currently the only effective treatment for morbid obesity with a proven mortality benefit is
surgical intervention. The underlying mechanisms of these surgical techniques are unclear …

The clinical efficacy and safety of medical devices for the treatment of obesity and type 2
diabetes mellitus (T2DM) has increased in the past decade. Medical devices intervene on …

Background: Vertical sleeve gastrectomy (VSG) causes rapid weight loss and improved
glucose regulation but also adverse moodrelated effects in a minority of patients. The vagus …

This study was designed to investigate whether transcutaneous auricular vagal nerve
stimulation (taVNS) would be able to improve major pathophysiologies of functional …