HaloTag as a reporter gene for PET
1092 Objectives To employ HaloTag technology for positron emission tomography (PET),
which involves 2 components: HaloTag protein (an engineered haloalkane dehalogenase …
which involves 2 components: HaloTag protein (an engineered haloalkane dehalogenase …
[HTML][HTML] HaloTag as a reporter gene: positron emission tomography imaging with 64Cu-labeled second generation HaloTag ligands
The goal of this study is to employ the HaloTag technology for positron emission tomography
(PET), which involves two components: the HaloTag protein (a modified hydrolase which …
(PET), which involves two components: the HaloTag protein (a modified hydrolase which …
[HTML][HTML] HaloTag: a novel reporter gene for positron emission tomography
Among the many molecular imaging techniques, reporter gene imaging has been a dynamic
area of research. The HaloTag protein is a modified haloalkane dehalogenase which was …
area of research. The HaloTag protein is a modified haloalkane dehalogenase which was …
Dual-modality HaloTag ligands for SPECT/CT and optical imaging
1060 Objectives HaloTag® technology is based on the rapid and highly selective formation
of a covalent bond between HaloTag protein and a chloroalkane HaloTag ligand. The ability …
of a covalent bond between HaloTag protein and a chloroalkane HaloTag ligand. The ability …
In vivo pretargeted dual-modality imaging of HER2 and TAG-72 expression using the HaloTag enzyme
1210 Objectives The covalent bond-forming reaction that occurs between the dehalogenase
enzyme HaloTag and a chloroalkane HaloTag ligand (HTL) has been shown to proceed …
enzyme HaloTag and a chloroalkane HaloTag ligand (HTL) has been shown to proceed …
Application of HaloTag® Technology to in Vivo Molecular Imaging Using Protein Probes Labeled by Metallic Radionuclides
S Kimura, Y Kakishima, T Kuchimaru… - …, 2016 - jstage.jst.go.jp
We are developing new protein probes for in vivo radionuclide imaging using HaloTag®
interchangeable labeling system. The selective and rapid bond formation between the …
interchangeable labeling system. The selective and rapid bond formation between the …
In vivo pretargeted imaging of HER2 and TAG-72 expression using the HaloTag enzyme
A novel pretargeted SPECT imaging strategy based on the HaloTag enzyme has been
evaluated for the first time in a living system. To determine the efficacy of this approach, two …
evaluated for the first time in a living system. To determine the efficacy of this approach, two …
Quantitative radioimmunoPET of EphA2 expression in xenograft-bearing mice
W Cai, A Ebrahimnejad, K Chen, D Tice, X Chen - 2007 - Soc Nuclear Med
83 Objectives: The receptor tyrosine kinase, EphA2 (Ephrin Receptor EphA2), is significantly
overexpressed in many cancer types and high EphA2 expression has been correlated with …
overexpressed in many cancer types and high EphA2 expression has been correlated with …
Quantitative radioimmunoPET imaging of EphA2 in tumor-bearing mice
W Cai, A Ebrahimnejad, K Chen, Q Cao, ZB Li… - European journal of …, 2007 - Springer
Purpose EphA2 receptor tyrosine kinase is significantly overexpressed in a wide variety of
cancer types. High EphA2 expression has been correlated with increased metastatic …
cancer types. High EphA2 expression has been correlated with increased metastatic …
68Ga-Labeled Small Molecule Inhibitor for c-Met Targeted PET imaging of Tumor.
C Liu, K Geng, H Zhu, A Zhang, Z Cheng - 2016 - Soc Nuclear Med
525 Objectives The mesenchymal epithelial transition (c-Met) factor overexpression has
been widely accepted as a potent biomarker for various of cancers such as glioblastoma …
been widely accepted as a potent biomarker for various of cancers such as glioblastoma …